Patents by Inventor Siegfried B. Christensen

Siegfried B. Christensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide deformylase inhibitors
    Patent number: 7919528
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Grant
    Filed: May 30, 2003
    Date of Patent: April 5, 2011
    Assignee: GlaxoSmithKline LLC
    Inventors: Kelly M. Aubart, Andrew B. Benowitz, Siegfried B. Christensen, IV, Joseph M. Karpinski, Jinhwa Lee, Domingos J. Silva
  • Peptide deformylase inhibitors
    Patent number: 7893056
    Abstract: The present invention is directed to certain {2-(alkyl)-3-[2-(5-fluoro-4-pyrimidinyl)hydrazino]-3-oxopropyl}hydroxyformamide derivatives, compositions containing them, the use of such compounds in the inhibition of bacterial peptide deformylase (PDF) activity, and in the treatment of bacterial infections. Specifically, the invention is directed to compounds of formula (I): wherein R1, R2 and R3 are defined herein and to pharmaceutically acceptable salts thereof. The compounds of this invention are bacterial peptide deformylase inhibitors and can be useful in the treatment of bacterial infections.
    Type: Grant
    Filed: November 6, 2008
    Date of Patent: February 22, 2011
    Assignee: GlaxoSmithKline LLC
    Inventors: Donghui Qin, Beth Norton, Andrew Nicholas Knox, Siegfried B. Christensen, Kelly M. Aubart
  • PEPTIDE DEFORMYLASE INHIBITORS
    Publication number: 20090306066
    Abstract: The present invention is directed to certain {2-(alkyl)-3-[2-(5-fluoro-4-pyrimidinyl)hydrazino]-3-oxopropyl}hydroxyformamide derivatives, compositions containing them, the use of such compounds in the inhibition of bacterial peptide deformylase (PDF) activity, and in the treatment of bacterial infections. Specifically, the invention is directed to compounds of formula (I): wherein R1, R2 and R3 are defined herein and to pharmaceutically acceptable salts thereof. The compounds of this invention are bacterial peptide deformylase inhibitors and can be useful in the treatment of bacterial infections.
    Type: Application
    Filed: November 6, 2008
    Publication date: December 10, 2009
    Inventors: Donghui Qin, Beth Norton, Andrew Nicholas Knox, Siegfried B. Christensen, Kelly M. Aubart
  • Peptide deformylase inhibitors
    Patent number: 7507726
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: March 24, 2009
    Assignee: SmithKlineBeecham Corporation
    Inventors: Kelly M. Aubart, Andrew B. Benowitz, Siegfried B. Christensen, IV, Jinhwa Lee, Domingos J. Silva
  • Peptide deformylase inhibitors
    Patent number: 7456211
    Abstract: The present invention involves novel anti-bacterial compounds represented by Formula (I), pharmaceutical compositions thereof, their use as PDF inhibitors, and their use in the treatment of bacterial infections.
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: November 25, 2008
    Assignee: SmithKline Beecham Corp
    Inventors: Kelly M. Aubart, Jia-Ning Xiang, Siegfried B. Christensen, IV, Xiangmin Liao, Maxwell D. Cummings
  • Peptide deformylase inhibitors
    Patent number: 7442793
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: October 28, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Jinhwa Lee, Siegfried B. Christensen, IV
  • Peptide Deformylase Inhibitors
    Publication number: 20080167302
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Application
    Filed: August 12, 2004
    Publication date: July 10, 2008
    Inventors: Kelly M. Aubart, Andrew B. Benowitz, Siegfried B. Christensen IV, Jinhwa Lee, Domingos J. Silva
  • Peptide deformylase inhibitors
    Patent number: 7375120
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: May 20, 2008
    Assignee: Smithkline Beecham Corporation
    Inventors: Siegfried B. Christensen, IV, Maxwell D. Cummings, Jinhwa Lee, Jia-ning Xiang
  • Peptide deformylase inhibitors
    Patent number: 7166624
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: January 23, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Jack Dale Leber, Mei Li, Jinhwa Lee, Kelly M. Aubart, Siegfried B. Christensen, IV
  • Peptide deformylase inhibitors
    Patent number: 7115605
    Abstract: PDF inhibitors and novel methods for their use are provided.
    Type: Grant
    Filed: April 5, 2004
    Date of Patent: October 3, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Kelly M. Aubart, Siegfried B. Christensen, IV, Jacques Briand, Maxwell David Cummings
  • Peptide deformylase inhibitors
    Patent number: 7019003
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: March 28, 2006
    Assignee: Smithkline Beecham Corporation
    Inventors: Jia-Ning Xiang, Siegfried B. Christensen, IV, Jinhwa Lee, Daniel J. Mercer
  • Peptide deformylase inhibitors
    Patent number: 6967220
    Abstract: PDF inhibitors and novel methods for their use are provided.
    Type: Grant
    Filed: April 4, 2002
    Date of Patent: November 22, 2005
    Assignee: SmithKline Beecham Corporation
    Inventors: Ajita Bhat, Siegfried B. Christensen, IV, James S. Frazee, Martha S. Head, Jack D. Leber, Mei Li
  • Peptide deformylase inhibitors
    Patent number: 6897233
    Abstract: PDF inhibitors and novel methods for their use are provided.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: May 24, 2005
    Assignee: SmithKline Beecham Corporation
    Inventors: Jia-Ning Xiang, Siegfried B. Christensen, IV, Xiangmin Liao, Maxwell D. Cummings
  • Peptide deformylase inhibitors
    Patent number: 6852882
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Grant
    Filed: June 4, 2002
    Date of Patent: February 8, 2005
    Assignee: SmithKline Beecham Corporation
    Inventors: Siegfried B. Christensen, IV, Maxwell D. Cummings, Joseph M. Karpinski
  • Peptide deformylase inhibitors
    Publication number: 20040267015
    Abstract: PDF inhibitors and novel methods for their use are provided.
    Type: Application
    Filed: September 29, 2003
    Publication date: December 30, 2004
    Inventors: Ajita Bhat, Siegfried B. Christensen, James S. Frazee, Martha S. Head, Jack D. Leber, Mei Li
  • Peptide deformylase inhibitors
    Patent number: 6806369
    Abstract: PDF inhibitors and novel methods for their use are provided.
    Type: Grant
    Filed: November 5, 2002
    Date of Patent: October 19, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: Kelly M. Aubart, Siegfried B. Christensen, IV, Jacques Briand, Maxwell David Cummings
  • Peptide deformylase inhibitors
    Publication number: 20040192719
    Abstract: PDF inhibitors and novel methods for their use are provided.
    Type: Application
    Filed: April 5, 2004
    Publication date: September 30, 2004
    Applicant: SmithKline Beecham Corporation
    Inventors: Kelly M. Aubart, Siegfried B. Christensen, Jacques Briand, Maxwell David Cummings
  • Peptide deformylase inhibitors
    Patent number: 6797730
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Grant
    Filed: February 18, 2004
    Date of Patent: September 28, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: Jia-Ning Xiang, Siegfried B. Christensen, IV, Jinhwa Lee
  • Peptide deformylase inhibitors
    Publication number: 20040157916
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Application
    Filed: November 17, 2003
    Publication date: August 12, 2004
    Inventors: Siegfried B. Christensen IV, Maxwell D. Cummings, Joseph M. Karpinski
  • PEPTIDE DEFORMYLASE INHIBITORS
    Publication number: 20040133001
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Application
    Filed: February 18, 2004
    Publication date: July 8, 2004
    Inventors: Jia-Ning Xiang, Siegfried B. Christensen IV, Jinhwa Lee