Patents by Inventor Siegfried Noetzel

Siegfried Noetzel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7993607
    Abstract: The invention concerns plasma separation on a microliter scale. The method/system according to the invention is able to provide plasma in the range of several microliters within a very short time as it is required, for example, in modern analyses by carrier-bound test elements. Plasma separation and plasma release is carried out in two separate consecutive steps of the method using the device according to the invention such that hemolysis during plasma separation can be avoided despite an accelerated procedure. The device comprises a disposable unit in which the device is characterized by an economical and simple method of production.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: August 9, 2011
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Guenter Frey, Norbert Ladiges, Siegfried Noetzel, Bernd Roesicke
  • Patent number: 7641862
    Abstract: An analytical test element for blood analyses is provided having an application site and a microfluidic channel structure in fluid communication with the application site. The channel structure includes at least first and second analytical channels for receiving first and second portions of a blood sample applied to the application site. The first analytical channel includes a first analytical site to determine the total haemoglobin value (Hb) of the blood sample. The second analytical channel includes a second analytical site to determine a glycohaemoglobin value (HbA1c) of the blood sample.
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: January 5, 2010
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Siegfried Noetzel, Jean-Philippe Bogardi, Dieter Mangold
  • Publication number: 20090155762
    Abstract: The invention concerns plasma separation on a microliter scale. The method/system according to the invention is able to provide plasma in the range of several microliters within a very short time as it is required, for example, in modern analyses by carrier-bound test elements. Plasma separation and plasma release is carried out in two separate consecutive steps of the method using the device according to the invention such that hemolysis during plasma separation can be avoided despite an accelerated procedure. The device comprises a disposable unit in which the device is characterized by an economical and simple method of production.
    Type: Application
    Filed: June 18, 2008
    Publication date: June 18, 2009
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Guenter Frey, Norbert Ladiges, Siegfried Noetzel, Bernd Roesicke
  • Publication number: 20090087901
    Abstract: An analytical test element for blood analyses is provided having an application site and a microfluidic channel structure in fluid communication with the application site. The channel structure comprises at least first and second analytical channels for receiving first and second portions of a blood sample applied to the application site. The first analytical channel comprises a first analytical site to determine the total haemoglobin value (Hb) of the blood sample. The second analytical channel comprises a second analytical site to determine a glycohaemoglobin value (HbA1c) of the blood sample.
    Type: Application
    Filed: December 9, 2008
    Publication date: April 2, 2009
    Inventors: Siegfried Noetzel, Jean-Philippe Bogardi, Dieter Mangold
  • Patent number: 7479393
    Abstract: An analytical test element for blood analyses is provided having at least a substrate body having a channel structure for the flow transport of a blood sample from an application site to at least one analytical site. The channel structure has a dilution channel that can be loaded with the blood sample and is provided with a separation component for retaining corpuscular blood components and has a sample channel which conveys a blood sample aliquot to be diluted and joins the dilution channel at a mixing site.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: January 20, 2009
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Siegfried Noetzel, Jean-Philippe Bogardi, Dieter Mangold
  • Patent number: 7404931
    Abstract: The invention concerns plasma separation on a microliter scale. The method/system according to the invention is able to provide plasma in the range of several microliters within a very short time as it is required, for example, in modern analyses by carrier-bound test elements. Plasma separation and plasma release is carried out in two separate consecutive steps of the method using the device according to the invention such that hemolysis during plasma separation can be avoided despite an accelerated procedure. The device comprises a disposable unit in which the device is characterized by an economical and simple method of production.
    Type: Grant
    Filed: November 10, 2003
    Date of Patent: July 29, 2008
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Guenter Frey, Norbert Ladiges, Siegfried Noetzel, Bernd Roesicke
  • Publication number: 20040222168
    Abstract: The invention concerns plasma separation on a microliter scale. The method/system according to the invention is able to provide plasma in the range of several microliters within a very short time as it is required, for example, in modern analyses by carrier-bound test elements. Plasma separation and plasma release is carried out in two separate consecutive steps of the method using the device according to the invention such that hemolysis during plasma separation can be avoided despite an accelerated procedure. The device comprises a disposable unit in which the device is characterized by an economical and simple method of production.
    Type: Application
    Filed: November 10, 2003
    Publication date: November 11, 2004
    Inventors: Guenter Frey, Norbert Ladiges, Siegfried Noetzel, Bernd Roesicke
  • Publication number: 20040191124
    Abstract: For an analytical test element for blood analyses comprising a substrate body having a channel structure for the flow transport of a blood sample from an application site to at least one analytical site, the invention proposes that the channel structure has a dilution channel that can be loaded with the blood sample and is provided with separation means for retaining corpuscular blood components and has a sample channel which conveys a blood sample aliquot to be diluted and joins the dilution channel at a mixing site.
    Type: Application
    Filed: February 6, 2004
    Publication date: September 30, 2004
    Inventors: Siegfried Noetzel, Jean-Philippe Bogardi, Dieter Mangold
  • Patent number: 5177022
    Abstract: The present invention provides an immune reactive porous carrier material comprising a porous carrier material with immune complexes precipitated thereon, wherein the porous carrier material is treated with at least one wet-strength agent.The present invention also provides processes for the production of this immune reactive porous carrier material.
    Type: Grant
    Filed: August 25, 1988
    Date of Patent: January 5, 1993
    Assignee: Boehringer Mannheim GmbH
    Inventors: Dieter Mangold, Siegfried Noetzel, Rolf Lerch, Jelmut Jering
  • Patent number: 5079156
    Abstract: The invention relates to crosslinked polymers based on polyvinyl acylate or polyvinyl alcohol and having crosslinking agent units which are derived from crosslinking agents of the general formulae ##STR1## These products, inter alia, are particularly hydrolysis-resistant and can have high crosslinking densities.The invention also relates to a process for preparing these polymers and to their use in chromatography and as carriers for biologically active substances.
    Type: Grant
    Filed: August 31, 1988
    Date of Patent: January 7, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Otto Mauz, Siegfried Noetzel, Bernhard Neumann
  • Patent number: 4931476
    Abstract: Crosslinked polymers which are produced from monomers containing epoxide groups, crosslinking monomers and, where appropriate, other monoethylenically unsaturated monomers are composed of principally spherical porous particles and are very suitable as carrier materials for the immobilization of biologically active substances.
    Type: Grant
    Filed: August 26, 1987
    Date of Patent: June 5, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Otto Mauz, Siegfried Noetzel, Klaus Sauber
  • Patent number: 4906715
    Abstract: The invention relates to crosslinked polymers based on polyvinyl acylate or polyvinyl alcohol and having crosslinking agent units which are derived from crosslinking agents of the general formulae ##STR1## and/or ##STR2## These products, inter alia, are particularly hydrolysis-resistant and can have high crosslinking densities.The invention also relates to a process for preparing these polymers and to their use in chromatography and as carriers for biologically active substances.
    Type: Grant
    Filed: December 8, 1987
    Date of Patent: March 6, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Otto Mauz, Siegfried Noetzel, Bernhard Neumann
  • Patent number: 4767620
    Abstract: Crosslinked polymers which are produced from monomers containing glycerol carbonate groups, crosslinking monomers and, where appropriate, other monoethylenically unsaturated monomers are composed of principally spherical porous particles and are very suitable as carrier materials for the immobilization of biologically active substances.
    Type: Grant
    Filed: August 26, 1987
    Date of Patent: August 30, 1988
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Otto Mauz, Siegfried Noetzel, Klaus Sauber
  • Patent number: 4568706
    Abstract: The invention relates to bead polymers based on monomers of the formula ##STR1## in which X is hydrogen or methyl, R denotes an aliphatic hydrocarbon radical having 1 to 12 carbon atoms, and Y denotes OH or NH.sub.2, which have been prepared using a special dispersion stabilizer. They are particularly distinguished by high porosity and are very suitable as carrier materials for biologically active substances.
    Type: Grant
    Filed: May 25, 1984
    Date of Patent: February 4, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Siegfried Noetzel, Otto Mauz, Klaus Sauber
  • Patent number: 4542069
    Abstract: The invention relates to bead polymers based on vinylene carbonate which are distinguished, in particular, by high porosity and which are well suited as carrier materials for biologically active substances.The preparation of these bead polymers is carried out, according to the invention, in the presence of certain dispersion stabilizers.
    Type: Grant
    Filed: November 23, 1983
    Date of Patent: September 17, 1985
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Otto Mauz, Klaus Sauber, Siegfried Noetzel
  • Patent number: 4166161
    Abstract: There are described expandable molding compositions of styrene polymers containing 1,2,3,4,5,6-hexabromohexene-1 or 1,2,3,4,5,6-hexabromohexene-3 or mixtures thereof as the flame-retarding agent, and showing a favorable combination of improved properties, especially high pre-foaming velocity, good welding, rapid mold-releasing and good flame-retardance.
    Type: Grant
    Filed: May 25, 1978
    Date of Patent: August 28, 1979
    Assignee: Hoechst Aktiengesellschaft
    Inventor: Siegfried Noetzel
  • Patent number: 4111900
    Abstract: There are disclosed novel flame-proofing agents for plastics, especially for homopolymers and copolymers of styrene and acrylonitrile. These agents are organic compounds containing bromine and one or two phosphinic acid groups. Besides the good flame-retarding properties these compounds have the advantage that they do not adversely affect the shrinking of foamed plastics.
    Type: Grant
    Filed: September 17, 1976
    Date of Patent: September 5, 1978
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Siegfried Noetzel, Horst Jastrow, Rudolf Uebe
  • Patent number: 4098759
    Abstract: Bromine-containing phosphonic acid esters of the formula ##STR1## in which R represents a halogen-containing linear or branched aliphatic or cycloaliphatic hydrocarbon radical having from 1 to 8 carbon atoms and R' and R" are hydrogen, halogen or alkyl groups having from 1 to 4 carbon atoms which may be closed to form a ring and/or substituted by halogen, at least one substituent being a bromine atom, are suitable as flame retardants for plastic materials, especially polystyrene and styrene copolymers.
    Type: Grant
    Filed: January 27, 1976
    Date of Patent: July 4, 1978
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Siegfried Noetzel, Horst Jastrow, Edgar Fischer
  • Patent number: 4036811
    Abstract: There are disclosed novel flame retarding polyamide molding compositions containing, as the flameproofing agents, an amount of from 6 to 40, preferably 8 to 30 weight % of an alkali metal or a group II or III metal salt of a phosphinic or diphosphinic acid. The flameproofing agents are thermostable and do not adversely affect the polyamides during preparation and processing.
    Type: Grant
    Filed: October 6, 1975
    Date of Patent: July 19, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Siegfried Noetzel, Walter Herwig
  • Patent number: 4010225
    Abstract: Bromine containing telomeric phosphonic acid esters of the formula ##STR1## which are used as flameproofing agent for the preparation of flame-repellent thermoplastic compositions.
    Type: Grant
    Filed: September 3, 1975
    Date of Patent: March 1, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Siegfried Noetzel, Horst Jastrow, Edgar Fischer