Abstract: Skin hydration is necessary to maintain the epidermal barrier, minimize adverse environmental influences, and reduce cell stress. Provided herein are compounds, such as compounds of Formula (I), and pharmaceutically and cosmetically acceptable salts thereof, and compositions, methods, and uses that may be used for skin hydration. Also reported herein is a scalable method for synthesizing compounds of Formula (I). The compounds provided herein are responsible for improved skin penetration and/or retention and are therefore useful for the treatment and/or prevention of various diseases, disorders, or conditions to protect human skin.

Abstract: An apparatus comprising: a memory; at least one processor operatively coupled to the memory, configured to: execute a plurality of platforms that are different from each other in at least one of type and version, each of the platforms being associated with one or more respective applications; and perform an operation including at least one of deleting a first platform, installing a second platform, deleting a first application from one of the platforms, and installing a second application in one of the platforms.

Abstract: An apparatus comprising: a memory; at least one processor operatively coupled to the memory, configured to: execute a plurality of platforms that are different from each other in at least one of type and version, each of the platforms being associated with one or more respective applications; and perform an operation including at least one of deleting a first platform, installing a second platform, deleting a first application from one of the platforms, and installing a second application in one of the platforms.