Patents by Inventor Sigalit Shaprut

Sigalit Shaprut has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tissue engineered biografts for repair of damaged myocardium
    Patent number: 7214371
    Abstract: The invention is directed to tissue-engineered biografts, methods for preparing the biografts of the invention, and methods for repairing a damaged myocardium in a mammal. The methods of the invention can include providing a three-dimensional porous polysaccharide matrix; introducing mammalian cells into said matrix; growing said cells in said matrix in vitro, until a tissue-engineered biograft is formed; and transplanting the tissue-engineered biograft onto myocardial tissue or myocardial scar tissue of said mammal. The tissue-engineered biograft of the invention can form a contracting tissue. The methods of the invention can optionally include removing scar tissue or dead tissue from the site of implantation prior to transplanting the biograft.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: May 8, 2007
    Assignee: Ben-Gurion University of the Negev Research & Development Authority
    Inventors: Smadar Cohen, Ayelet Dar, Sharon Etzion, Anat Perets, Sigalit Shaprut, Jonathan Leor
  • ENGINEERED BIOGRAFTS FOR REPAIR OF DAMAGED MYOCARDIUM
    Publication number: 20070014772
    Abstract: A method for repairing a damaged myocardium in a mammal, comprising: a) providing a three-dimensional porous polysaccharide matrix; b) introducing mammalian cells into said matrix; c) growing said cells in said matrix in vitro, until a tissue-engineered biograft is formed, comprising a contracting tissue; and d) transplanting the tissue-engineered biograft onto the myocardial tissue or myocardial scar tissue of said mammal, optionally previously removing scar or dead tissue from the site of implantation.
    Type: Application
    Filed: September 25, 2006
    Publication date: January 18, 2007
    Applicant: Ben-Gurion University of the Negev
    Inventors: Smadar Cohen, Ayelet Dar, Sharon Etzion, Anat Perets, Sigalit Shaprut, Jonathan Leor