Patents by Inventor Sigrid Milles

Sigrid Milles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing self-assembling paramyxoviral nucleocapsid-like particles and their uses
    Patent number: 11319350
    Abstract: Embodiments of the disclosure relate to the domain of virology of Paramyxoviruses. The disclosure concerns a method for producing self-assembling paramyxoviral particles and a method for identifying a compound able to inhibit the replication or the transcription of a Paramyxovirus. The disclosure also pertains to the nucleocapsid-like particles obtainable by the method of the invention and their use for biotechnological and pharmaceutical applications.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: May 3, 2022
    Assignees: Centre National De La Recherche Scientifique, Universite Grenoble Alpes, Commissariat A L'Energie Atomique Et Aux Energies Alternatives
    Inventors: Martin Blackledge, Marlène Ringkjobing-Jensen, Sigrid Milles, Robertus Ruigrok, Guy Schoehn, Guillaume Communie
  • METHOD FOR PRODUCING SELF-ASSEMBLING PARAMYXOVIRAL NUCLEOCAPSID-LIKE PARTICLES AND THEIR USES
    Publication number: 20190292229
    Abstract: Embodiments of the disclosure relate to the domain of virology of Paramyxoviruses. The disclosure concerns a method for producing self-assembling paramyxoviral particles and a method for identifying a compound able to inhibit the replication or the transcription of a Paramyxovirus. The disclosure also pertains to the nucleocapsid-like particles obtainable by the method of the invention and their use for biotechnological and pharmaceutical applications.
    Type: Application
    Filed: June 6, 2017
    Publication date: September 26, 2019
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Martin Blackledge, Marlène Ringkjobing-Jensen, Sigrid Milles, Robertus Ruigrok, Guy Schoehn, Guillaume Communie
  • Unnatural amino acids comprising a cyclooctynyl or trans-cyclooctenyl analog group and uses thereof
    Patent number: 9085514
    Abstract: The present invention relates to unnatural amino acids comprising a cyclooctynyl or trans-cyclooctenyl analog group and having formula (I) or an acid or base addition salt thereof. The invention also relates to the use of said unnatural amino acids, kits and processes for preparation of polypeptides that comprise one or more than one cyclooctynyl or trans-cyclooctenyl analog group. These polypeptides can be covalently modified by in vitro or in vivo reaction with compounds comprising an azide, nitrile oxide, nitrone, diazocarbonyl or 1,2,4,5-tetrazine group.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: July 21, 2015
    Assignee: EMBL
    Inventors: Edward Lemke, Carsten Schultz, Tilman Plass, Sigrid Milles, Christine Koehler
  • UNNATURAL AMINO ACIDS COMPRISING A CYCLOOCTYNYL OR TRANS-CYCLOOCTENYL ANALOG GROUP AND USES THEREOF
    Publication number: 20140073764
    Abstract: The present invention relates to unnatural amino acids comprising a cyclooctynyl or trans-cyclooctenyl analog group and having formula (I) or an acid or base addition salt thereof. The invention also relates to the use of said unnatural amino acids, kits and processes for preparation of polypeptides that comprise one or more than one cyclooctynyl or trans-cyclooctenyl analog group. These polypeptides can be covalently modified by in vitro or in vivo reaction with compounds comprising an azide, nitrile oxide, nitrone, diazocarbonyl or 1,2,4,5-tetrazine group.
    Type: Application
    Filed: February 3, 2012
    Publication date: March 13, 2014
    Applicant: EMBL
    Inventors: Edward Lemke, Carsten Schultz, Tilman Plass, Sigrid Milles, Christine Koehler