Patents by Inventor Sigrid Paech

Sigrid Paech has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mass spectrometric analysis of biopolymers
    Patent number: 7396688
    Abstract: The present invention makes use of unique tags of a specific biopolymer that can be exploited for determining the concentration the biopolymer in crude solutions. In preferred embodiments the biopolymer is either a protein or a polynucleotide. Particularly, the invention provides a method for the determination and quantitation of biomolecules in crude mixtures by way of a separation technique in combination with mass spectroscopy. In one general embodiment, a target biomolecule is selected for analysis and an analog thereof is generated. Peak area integration of the peptide pairs provides a direct measure for the amount of target protein in the crude solution.
    Type: Grant
    Filed: December 14, 2004
    Date of Patent: July 8, 2008
    Assignee: Genencor International, Inc.
    Inventors: David A. Estell, Grant C. Ganshaw, Christian Paech, Sigrid Paech
  • Mass spectrometric analysis of biopolymers
    Publication number: 20050244848
    Abstract: The present invention makes use of unique tags of a specific biopolymer that can be exploited for determining the concentration the biopolymer in crude solutions. In preferred embodiments the biopolymer is either a protein or a polynucleotide. Particularly, the invention provides a method for the determination and quantitation of biomolecules in crude mixtures by way of a separation technique in combination with mass spectroscopy. In one general embodiment, a target biomolecule is selected for analysis and an analog thereof is generated. Peak area integration of the peptide pairs provides a direct measure for the amount of target protein in the crude solution.
    Type: Application
    Filed: December 14, 2004
    Publication date: November 3, 2005
    Inventors: David Estell, Grant Ganshaw, Christian Paech, Sigrid Paech
  • Mass spectrometric analysis of biopolymers
    Publication number: 20020123055
    Abstract: The present invention makes use of unique tags of a specific biopolymer that can be exploited for determining the concentration the biopolymer in crude solutions. In preferred embodiments the biopolymer is either a protein or a polynucleotide. Particularly, the invention provides a method for the determination and quantitation of biomolecules in crude mixtures by way of a separation technique in combination with mass spectroscopy. In one general embodiment, a target biomolecule is selected for analysis and an analog thereof is generated. Peak area integration of the peptide pairs provides a direct measure for the amount of target protein in the crude solution.
    Type: Application
    Filed: August 17, 2001
    Publication date: September 5, 2002
    Inventors: David A. Estell, Grant C. Ganshaw, Christian Paech, Sigrid Paech