Patents by Inventor Sigui CHEN

Sigui CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF
    Publication number: 20230157996
    Abstract: The present application provides a small-molecule inhibitor targeting an EB virus nuclear antigen protein, and/or a pharmaceutical composition containing the same, which can be used for the treatment of a disease caused by EBNA1 activity, such as, but not limited to, cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and/or rheumatoid arthritis. The present application further provides a small-molecule inhibitor targeting an EB virus nuclear antigen protein, and/or a pharmaceutical composition containing the same, which can be used for the treatment of a disease caused by EBV infection in a lytic and/or latent phase.
    Type: Application
    Filed: December 2, 2022
    Publication date: May 25, 2023
    Applicants: Shenzhen Bay Laboratory, Peking University Shenzhen Graduate School
    Inventors: Zhendong ZHU, Zhengshuang XU, Ting LI, Chao CHE, Qingzhou ZHANG, Sigui CHEN, Huangcan CHEN, Dehu XIANG, Zhen YANG