Patents by Inventor Siguo LIU

Siguo LIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for positioning and integrating transgene and use thereof
    Patent number: 10036041
    Abstract: Provided in the present invention is a method for positioning and integrating transgene and a use thereof. Specifically provided is a variant loxP element. The sequence “ATAAT” of an reverse repeated sequence in a wild type loxp locus is mutated into “CACCT”, i.e., a variant loxp element. Also provided in the present invention are a construct comprising the variant loxP element, a vector or host cell comprising the construct and a method for preparing a transgenic animal using the vector and the host cell.
    Type: Grant
    Filed: September 28, 2013
    Date of Patent: July 31, 2018
    Assignees: SHANGHAI GENON BIOENGINEERING CO., LTD, SHANGHAI TRANSGENIC RESEARCH CENTER
    Inventors: Guoxiang Cheng, Jianquan Chen, Siguo Liu
  • METHOD FOR POSITIONING AND INTEGRATING TRANSGENE AND USE THEREOF
    Publication number: 20160304906
    Abstract: Provided in the present invention is a method for positioning and integrating transgene and a use thereof. Specifically provided is a variant loxP element. The sequence “ATAAT” of an reverse repeated sequence in a wild type loxp locus is mutated into “CACCT”, i.e., a variant loxp element. Also provided in the present invention are a construct comprising the variant loxP element, a vector or host cell comprising the construct and a method for preparing a transgenic animal using the vector and the host cell.
    Type: Application
    Filed: September 28, 2013
    Publication date: October 20, 2016
    Inventors: Guoxiang CHENG, Jianquan CHEN, Siguo LIU