Abstract: The invention relates to a method for monitoring renal disease in a subject, comprising subjecting a sample comprising albumin from that subject to electrophoresis, preferably capillary electrophoresis, wherein carbamylated albumin is used as a bio-marker for the monitoring of the renal disease, which is preferably achieved by measuring the symmetry of the albumin peak in the assay. The invention further comprises the use of capillary electrophoresis for determining the amount of carbamylated albumin. Also claimed is a system for the determination of carbamylated serum albumin.