Patents by Inventor Sihe Zhang

Sihe Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Variable region gene of heavy/light chain of anti-human hepatoma monoclonal antibody HAb 18 and use thereof
    Patent number: 7638619
    Abstract: The present invention relates to the anti-human hepatocarcinoma McAb HAb18 heavy chain and light chain variable region genes, the polypeptides encoded by the same, as well as to their use in the preparation of a medicament for diagnosing and treating tumors or inflammation diseases. Based on the heavy chain and light chain variable region genes, various novel small molecule genetic engineering antibodies, including single chain antibodies, chimeric antibodies, Fab antibodies and the like can be constructed and expressed for the diagnosis and treatment of hepatoma.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: December 29, 2009
    Inventors: Zhinan Chen, Jinliang Xing, Sihe Zhang
  • Anti-human hepatoma monoclonal antibody hav18 light/heavy chain available region gene, and use thereof
    Publication number: 20050176933
    Abstract: The present invention relates to the anti-human hepatocarcinoma McAb HAb18 heavy chain and light chain variable region genes, the polypeptides encoded by the same, as well as to their use in the preparation of a medicament for diagnosing and treating tumors or inflammation diseases. Based on the heavy chain and light chain variable region genes, various novel small molecule genetic engineering antibodies, including single chain antibodies, chimeric antibodies, Fab antibodies and the like can be constructed and expressed for the diagnosis and treatment of hepatoma.
    Type: Application
    Filed: March 17, 2003
    Publication date: August 11, 2005
    Inventors: Zhinan Chen, Jinliang Xing, Sihe Zhang