Abstract: A precursor resin mixture for forming a multimaterial includes a multifunctional monomer comprising two or more first functional groups bonded to a base molecule and two or more terminal functional groups having a double-bonded carbon, a multifunctional thiol monomer having one or more second functional groups positioned between terminal thiol groups, and epoxy monomer, and a curing agent. Regarding the multifunctional monomer, the terminal functional groups being different than the first functional groups.

Abstract: In one general embodiment, a method includes, during performance of an additive manufacturing process that includes photocuring of a resin, monitoring light output generated by a fluorophore in the resin that exhibits aggregation-induced emission (AIE) behavior. An indication of an extent of photocuring is output based on the monitored light output. In another general embodiment, a resin for additive manufacturing includes molecules configured for photopolymerization and/or photocuring, the molecules being selected from the group consisting of monomers, oligomers, and polymers; a photoinitiator; and a fluorophore that exhibits aggregation-induced emission (AIE) behavior. The fluorophore is present in an amount of at least 0.00005 wt % relative to a total weight of the resin. In yet another general embodiment, a three-dimensional encrypted structure includes a fluorophore that exhibits aggregation-induced emission (AIE) behavior.

Abstract: A computer-implemented method for replicating a log to a remote computer system is disclosed. The method involves identifying a log comprising a data portion and a metadata portion for replication. The data portion is sent to the remote computer system using a Remote Direct Memory Access (RDMA) write operation, while the metadata portion is sent using a first RDMA send operation after the data portion has been sent. The method further includes identifying a second RDMA send operation received from the remote computer system, which indicates the completion of the first RDMA send operation. Based on identifying the second RDMA send operation, the method determines the completion of log replication to the remote computer system. This method enables efficient and reliable replication of logs in a computer system.

Abstract: Caching write input/output (I/O) operations in a replica-based storage system. A write I/O operation is received from a consumer, and a corresponding replica list is identified. A first replica set is selected from the replica list for caching the I/O operation, and a first log corresponding to the I/O operation is added to a primary ring buffer of the first replica set. When the first log cannot be replicated to a secondary ring buffer of the first replica set, a second replica set is selected from the replica list for caching the I/O operation. A second log corresponding to the I/O operation is added to a primary ring buffer of the second replica set. Once the second log has been replicated to a secondary ring buffer of the second replica set, the I/O operation is acknowledged to the consumer, and the second log is de-staged to a backing store.

Abstract: A product, in accordance with one aspect of the present invention, includes a porous first layer having a first porosity, and a porous skin layer having a second porosity that is relatively lower than the first porosity. The skin layer is a self-formed layer. A method, in accordance with one aspect of the present invention, includes contacting a resin with a separator. The resin is exposed to radiation for curing the resin, thereby simultaneously creating a porous first layer and a porous skin layer positioned between the first layer and the separator. The first layer has a first porosity. The skin layer has a second porosity that is relatively lower than the first porosity.

Abstract: A product includes a mixture for converting a polyurethane where the mixture includes a functional alcohol and a catalyst. A method of converting polyurethane includes forming a mixture at an ambient temperature where the mixture includes a polyurethane, a functional alcohol, and a catalyst. The method further includes collecting a product from the mixture after a duration of time. The product includes a diallyl urethane monomer and a multi-functional alcohol.

Abstract: Disclosed is a monoclonal antibody that binds human and monkey CD3, or an antigen-binding portion thereof, as well as the use of the antibody or antigen-binding portion thereof in treatment of inflammatory diseases and in preparation of bispecific antibodies. A bispecific antibody against e.g., CD3 and CD20 comprising the antibody or antigen-binding portion thereof of the disclosure, and the use of the bispecific antibody in treatment of diseases such as cancers are also provided.

Abstract: A player profile management system collects player data from various systems and generates and manages player profiles. A snapshot pipeline of the player profile management system generates a snapshot player profile associated with a player. The player profile management system receives, after generating the snapshot player profile associated with the player, player data associated with the player. An update pipeline of the player profile management system generates, based on the snapshot player profile and the player data associated with the player, an update player profile associated with the player.

Abstract: A player profile management system collects player data from various systems and generates and manages player profiles. A snapshot pipeline of the player profile management system generates a snapshot player profile associated with a player. The player profile management system receives, after generating the snapshot player profile associated with the player, player data associated with the player. An update pipeline of the player profile management system generates, based on the snapshot player profile and the player data associated with the player, an update player profile associated with the player.

Abstract: Described herein is a composition for producing a thiol-ene covalent adaptable network (CAN) polymer. The composition includes a first monomer including at least one thiol group; and a second monomer including at least one anhydride functional group and at least one alkene functional group. Also described herein are a polymer produced from the composition, a method of producing the polymer using the composition, a method of fabricating a polymer article using the composition, as well as a method of degrading the polymer.

Abstract: An antibody capable of blocking CD47-SIRPa interaction and an application thereof.

Abstract: A player profile management system collects player data from various systems and generates and manages player profiles. A snapshot pipeline of the player profile management system generates a snapshot player profile associated with a player. The player profile management system receives, after generating the snapshot player profile associated with the player, player data associated with the player. An update pipeline of the player profile management system generates, based on the snapshot player profile and the player data associated with the player, an update player profile associated with the player.

Abstract: A player profile management system collects player data from various systems and generates and manages player profiles. A snapshot pipeline of the player profile management system generates a snapshot player profile associated with a player. The player profile management system receives, after generating the snapshot player profile associated with the player, player data associated with the player. An update pipeline of the player profile management system generates, based on the snapshot player profile and the player data associated with the player, an update player profile associated with the player.

Abstract: The disclosure provides methods of generating a modulus gradient in a polymeric material, resin mixtures for such methods, and polymeric materials thereof having at least a modulus gradient.

Abstract: A player profile management system collects player data from various systems and generates and manages player profiles. A snapshot pipeline of the player profile management system generates a snapshot player profile associated with a player. The player profile management system receives, after generating the snapshot player profile associated with the player, player data associated with the player. An update pipeline of the player profile management system generates, based on the snapshot player profile and the player data associated with the player, an update player profile associated with the player.

Abstract: Disclosed is a monoclonal antibody that binds human and monkey CD3, or an antigen-binding portion thereof, as well as the use of the antibody or antigen-binding portion thereof in treatment of inflammatory diseases and in preparation of bispecific antibodies. A bispecific antibody against e.g., CD3 and CD20 comprising the antibody or antigen-binding portion thereof of the disclosure, and the use of the bispecific antibody in treatment of diseases such as cancers are also provided.

Abstract: An antibody capable of blocking CD47-SIRPa interaction and an application thereof.

Abstract: The present invention relates to humanized bispecific anti-HER2 antibodies that comprise one antigen binding site containing variable regions of heavy and light chain of trastuzumab, and another antigen binding site containing variable regions of heavy and light chain of pertuzumab. The bispecific anti-HER2 antibodies is effective for treating cancer, such as breast cancer, gastric cancer, or ovarian cancer. Preferred bispecific anti-HER antibodies of the present invention are afucosylated antibodies. The present invention also relates to Chinese Hamster ovary (CHO) mutant cell line that has a dysfunctional Slc35C1 gene, which is the only dysfunctional gene in the mutant that affects glycan regulation.

Abstract: The present invention relates to humanized bispecific anti-HER2 antibodies that comprise one antigen binding site containing variable regions of heavy and light chain of trastuzumab, and another antigen binding site containing variable regions of heavy and light chain of pertuzumab. The bispecific anti-HER2 antibodies is effective for treating cancer, such as breast cancer, gastric cancer, or ovarian cancer. Preferred bispecific anti-HER antibodies of the present invention are afucosylated antibodies. The present invention also relates to Chinese Hamster ovary (CHO) mutant cell line that has a dysfunctional Slc35C1 gene, which is the only dysfunctional gene in the mutant that affects glycan regulation.

Abstract: The present invention relates to humanized bispecific anti-HER2 antibodies that comprise one antigen binding site containing variable regions of heavy and light chain of trastuzumab, and another antigen binding site containing variable regions of heavy and light chain of pertuzumab. The bispecific anti-HER2 antibodies is effective for treating cancer, such as breast cancer, gastric cancer, or ovarian cancer. Preferred bispecific anti-HER antibodies of the present invention are afucosylated antibodies.