Abstract: An anti-CEA antibody-exatecan analog conjugate and a pharmaceutical use thereof. Specifically, the anti-CEA antibody-exatecan analog conjugate is as shown in general formula (Pc-L-Y-D), wherein Pc is an anti-CEA antibody or an antigen-binding fragment thereof; L is a linker unit; Y is selected from —O—(CRaRb)m—CR1R2—C(O)—, —O—CR1R2—(CRaRb)m—, —O—CR1R2—, —NH—(CRaRb)m—CR1R2—C(O)—, and —S—(CRaRb)m—CR1R2—C(O); and n is a decimal or integer from 1 to 10.

Abstract: An apertured nonwoven substrate is disclosed. The apertured nonwoven substrate has a first area having a first caliper, a second area having a plurality of apertures, and wherein the second area has a second caliper. A ratio of the first caliper to the second caliper is at least about 1.35, as measured according to Caliper Test, and the first area has an airy index no less than about 270%, as measured according to Caliper Test.

Abstract: The present disclosure relates to a nonwoven substrate comprising a plurality of apertures that form a pattern and define a plurality of discrete non-aperture zones. Each of the plurality of discrete non-aperture zones has a periphery formed by a continuous line of apertures, with adjacent apertures being spaced apart by an edge-to-edge distance of no more than 3 mm, while each of the plurality of discrete non-aperture zones is substantially free of apertures within the periphery. Particularly, the area ratio of such plurality of discrete non-aperture zones over the nonwoven substrate ranges from 60% to 90%, and at least some of said plurality of discrete non-aperture zones have an area of 100 mm2 or more.

Abstract: The present invention relates to a three-dimensional nonwoven comprising a first side, a second side, a protruded first area comprising an upper portion formed in the first side and a lower portion formed in the second side, and a second area comprising a plurality of deformations, wherein the upper portion has a shape memory index higher than a shape memory index of the lower portion, an absorbent article comprising the three-dimensional nonwoven, and a process for producing the three-dimensional nonwoven.

Abstract: Embodiments of the present disclosure relate to the field of communications technologies, and in particular, to a virtual reality (VR) interface generation method and an apparatus, to resolve a conventional problem of interface distortion, a twist, and image quality inconsistency when the interface is viewed by an observer. The method includes: obtaining head position information indicating a head position of an observer; generating a first user interface based on the head position information, where distances from all pixels on the first user interface to the observer are equal; and displaying a second user interface that is generated based on the first user interface.

Abstract: Methods and apparatuses are provided for continual few-shot learning. A model for a base task is generated with base classification weights for base classes of the base task. A series of novel tasks is sequentially received. Upon receiving each novel task in the series of novel tasks, the model is updated with novel classification weights for novel classes of the respective novel task. The novel classification weights are generated by a weight generator based on one or more of the base classification weights and, when one or more other novel tasks in the series are previously received, one or more other novel classification weights for novel classes of the one or more other novel tasks. Additionally, for each novel task, a first set of samples of the respective novel task are classified into the novel classes using the updated model.

Abstract: An assisted early screening system for Down syndrome, relating to assisted screening of Down syndrome skin prints based on a machine learning algorithm, wherein the system comprising: (a) a skin print feature input module; (b) a processing module for diagnosis of Down syndrome based on skin print, wherein the processing module performs a scoring processing on the inputted skin print features according to a predetermined evaluation criteria to obtain a risk score, and compares the risk score with a Down syndrome risk threshold, thereby obtaining an assisted screening result; and (c) an output module for assisted screening result, which is configured to output the assisted screening result. The assisted early screening system for Down syndrome can implement simple, accurate, and effective assisted early screening of Down syndrome, such that powerful assistance can be provided for postnatal early intervention for early Down syndrome patients.

Abstract: Embodiments of the present disclosure relate to the field of communications technologies, and in particular, to a virtual reality (VR) interface generation method and an apparatus, to resolve a conventional problem of interface distortion, a twist, and image quality inconsistency when the interface is viewed by an observer. The method includes: obtaining head position information indicating a head position of an observer; generating a first user interface based on the head position information, where distances from all pixels on the first user interface to the observer are equal; and displaying a second user interface that is generated based on the first user interface.

Abstract: The present invention relates to a method for inhibiting the formation of dioxin-like compounds in solid waste incineration flue gases, belonging to the field of cleaning of solid waste incineration flue gases. In accordance with the present invention, when incineration flue gases cool down to 500˜450° C., the flue gases are introduced into an inhibition reactor where copper chlorides in flue gas particulates mix and react with inhibitors to convert into copper metaphosphate so as to inactivate the copper chlorides which can catalyze the formation of dioxin-like compounds and control dioxin-like compound pollutants in incineration flue gases at the source. Compared with the prior art, the invention can effectively control the main formation ways of dioxin-like compounds in solid waste incineration flue gases by optimizing inhibitors and reaction conditions.

Abstract: The present invention relates to a method for inhibiting the formation of dioxin-like compounds in solid waste incineration flue gases, belonging to the field of cleaning of solid waste incineration flue gases. In accordance with the present invention, when incineration flue gases cool down to 500˜450° C., the flue gases are introduced into an inhibition reactor where copper chlorides in flue gas particulates mix and react with inhibitors to convert into copper metaphosphate so as to inactivate the copper chlorides which can catalyze the formation of dioxin-like compounds and control dioxin-like compound pollutants in incineration flue gases at the source. Compared with the prior art, the invention can effectively control the main formation ways of dioxin-like compounds in solid waste incineration flue gases by optimizing inhibitors and reaction conditions.

Abstract: A coating composition comprising a colloidal suspension comprising a fluoropolymer and fluorophilic particles in a liquid solvent, wherein the solvent comprises a fluorocarbon, a semifluorous material, or a combination thereof. Also disclosed is a substrate comprising a coated surface, wherein the coated surface comprises a fluorophilic silica particle doped—fluoropolymer film. Further disclosed is a method comprising fluorinating silica particles and preparing a colloidal suspension comprising a fluoropolymer and the fluorinated silica particles in a liquid solvent, wherein the solvent comprises a fluorocarbon, a semifluorous material, or a combination thereof.