Patents by Inventor Sijia Yi

Sijia Yi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS OF USING PROPYLENE SULFIDE-BASED POLYMERS FOR TREATMENT OF CHAGAS DISEASE
    Publication number: 20230330022
    Abstract: The present invention provides novel nanostructures comprising solution of PPSU20. Methods of preparing the novel PPSU nanostructures, and applications of such nanostructures are also provided.
    Type: Application
    Filed: July 3, 2023
    Publication date: October 19, 2023
    Inventors: Evan A. Scott, Sijia Yi, David Engman, Xiaomo Li
  • Compositions and methods of using propylene sulfide-based polymers for treatment of Chagas disease
    Patent number: 11737978
    Abstract: The present invention provides novel nanostructures comprising solution of PPSU20. Methods of preparing the novel PPSU nanostructures, and applications of such nanostructures are also provided.
    Type: Grant
    Filed: July 29, 2020
    Date of Patent: August 29, 2023
    Assignee: Northwestern University
    Inventors: Evan A. Scott, Sijia Yi, David Engman, Xiaomo Li
  • POLY(ETHYLENE GLYCOL)-BLOCK-POLY(PROPYLENE SULFIDE) NANOCARRIER PLATFORM FOR ENHANCED EFFICACY OF IMMUNOSUPPRESSIVE AGENTS
    Publication number: 20230263729
    Abstract: Provided herein are nanocarriers for delivery of immunosuppressive agents. In some embodiments, provided herein are nanocarriers comprising a core comprising a poly(ethylene glycol)-block-poly(propylene sulfide) copolymer and least one therapeutic agent. In some embodiments, the nanocarriers may further comprise a targeting ligand displayed on a surface of the nanocarrier. The at least one therapeutic agent may be an anti-inflammatory agent. The disclosed nanocarriers may be incorporated into pharmaceutical compositions for use in methods of treating an inflammatory condition or preventing transplantation rejection in a subject.
    Type: Application
    Filed: March 2, 2023
    Publication date: August 24, 2023
    Inventors: Evan A. Scott, Guillermo A. Ameer, Jacqueline A. Burke, Sean D. Allen, Sijia Yi
  • Nanostructure Enhanced Targeting (NSET) of Inflammatory Cells
    Publication number: 20210059938
    Abstract: The present invention provides nanomaterials for the specific targeting of immune cells. Methods of treating cardiac disease and inflammatory disease are also described.
    Type: Application
    Filed: October 30, 2020
    Publication date: March 4, 2021
    Inventors: Evan A. Scott, Sijia Yi, Sean D. Allen
  • COMPOSITIONS AND METHODS OF USING PROPYLENE SULFIDE-BASED POLYMERS FOR TREATMENT OF CHAGAS DISEASE
    Publication number: 20210052498
    Abstract: The present invention provides novel nanostructures comprising solution of PPSU20. Methods of preparing the novel PPSU nanostructures, and applications of such nanostructures are also provided.
    Type: Application
    Filed: July 29, 2020
    Publication date: February 25, 2021
    Applicant: Northwestern University
    Inventors: Evan A. Scott, Sijia Yi, Nicholas Karabin, Xiaomo Li
  • POLY(ETHYLENE GLYCOL)-BLOCK-POLY (PROPYLENE SULFIDE) NANOCARRIER PLATFORM FOR ENHANCED EFFICACY OF IMMUNOSUPPRESSIVE AGENTS
    Publication number: 20200383917
    Abstract: Provided herein are nanocarriers for delivery of immunosuppressive agents. In some embodiments, provided herein are nanocarriers comprising a core comprising a poly(ethylene glycol)-block-poly(propylene sulfide) copolymer and least one therapeutic agent. In some embodiments, the nanocarriers may further comprise a targeting ligand displayed on a surface of the nanocarrier. The at least one therapeutic agent may be an anti-inflammatory agent. The disclosed nanocarriers may be incorporated into pharmaceutical compositions for use in methods of treating an inflammatory condition or preventing transplantation rejection in a subject.
    Type: Application
    Filed: June 3, 2020
    Publication date: December 10, 2020
    Inventors: Evan A. Scott, Guillermo A. Ameer, Jacqueline A. Burke, Sean D. Allen, Sijia Yi
  • Nanostructure enhanced targeting (NSET) of inflammatory cells
    Patent number: 10821078
    Abstract: The present invention provides nanomaterials for the specific targeting of immune cells. Methods of treating cardiac disease and inflammatory disease are also described.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: November 3, 2020
    Assignee: Northwestern University
    Inventors: Evan A. Scott, Sijia Yi, Sean D. Allen
  • Nanostructure Enhanced Targeting (NSET) of Inflammatory Cells
    Publication number: 20180028446
    Abstract: The present invention provides nanomaterials for the specific targeting of immune cells. Methods of treating cardiac disease and inflammatory disease are also described.
    Type: Application
    Filed: June 29, 2017
    Publication date: February 1, 2018
    Inventors: Evan A. Scott, Sijia Yi, Sean D. Allen