Patents by Inventor Sijian Wang

Sijian Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230281565
    Abstract: A method for generating lower-dimension graph representations is disclosed. The may include obtaining a graph having at least one primary node, a plurality of secondary nodes, and a plurality of edges connecting the at least one primary node to the plurality of secondary nodes. Further, the method may include determining the graph as at least one of a sparse graph or a dense graph, using primary connectivity data and secondary connectivity data associated with the graph; and augmenting the graph with the secondary connectivity data to produce an augmented graph, based on the graph being the sparse graph. The secondary connectivity data may be indicative of a set of knowledge graphs associated with the plurality of secondary nodes. Furthermore, the method may include generating the lower-dimension graph representations for the augmented graph.
    Type: Application
    Filed: March 4, 2022
    Publication date: September 7, 2023
    Inventors: Yu ZHOU, Sijian WANG, Xinwen ZHANG
  • Patent number: 8126690
    Abstract: A method of using a variable set from complete blood counts and blood chemistry panels to generate a machine learned algorithm for determining the effectiveness of thiopurine treatment on inflammatory bowel disease (IBD) patients using CART, boosted trees, random forest classification, RuleFit and/or logistic regression analysis.
    Type: Grant
    Filed: May 18, 2007
    Date of Patent: February 28, 2012
    Assignee: The Regents of the University of Michigan
    Inventors: Peter Higgins, Ji Zhu, Akbar Waljee, Sijian Wang, Joel Joyce
  • Publication number: 20080288227
    Abstract: A method of using a variable set from complete blood counts and blood chemistry panels to generate a machine learned algorithm for determining the effectiveness of thiopurine treatment on inflammatory bowel disease (IBD) patients using CART, boosted trees, random forest classification, RuleFit and/or logistic regression analysis.
    Type: Application
    Filed: May 18, 2007
    Publication date: November 20, 2008
    Applicant: UNIVERSITY OF MICHIGAN
    Inventors: Peter Higgins, Ji Zhu, Akbar Waljee, Sijian Wang, Joel Joyce
  • Publication number: 20030202967
    Abstract: This invention relates to cell lines, particularly mammalian cell lines, established by transforming the cells with vectors, preferably retroviral vectors, containing two or more oncogenes under the control of one or more inducible promoters and/or genetic elements. Also within the scope of the invention are human cell lines with extended in vitro lifespan, transformed by vectors containing one or more oncogenes under the control of one or more, preferably exogenous, inducible promoters and/or genetic elements. The vectors may additionally contain gene(s) encoding for desired gene product(s). Also disclosed are insulin producing human pancreatic cell lines useful for transplantation into human diabetic patients.
    Type: Application
    Filed: March 27, 2003
    Publication date: October 30, 2003
    Applicants: The Regents of the University of California, Whittier Institute for Diabetes and Endocrinology
    Inventors: Fred Levine, Sijian Wang, Gillian M. Beattie, Alberto Hayek
  • Patent number: 6110743
    Abstract: This invention relates to cell lines, particularly mammalian cell lines, established by transforming the cells with vectors, preferably retroviral vectors, containing two or more oncogenes under the control of one or more inducible promoters and/or genetic elements. Also within the scope of the invention are human cell lines with extended in vitro lifespan, transformed by vectors containing one or more oncogenes under the control of one or more, preferably exogenous, inducible promoters and/or genetic elements. The vectors may additionally contain gene(s) encoding for desired gene product(s). Also disclosed are insulin producing human pancreatic cell lines useful for transplantation into human diabetic patients.
    Type: Grant
    Filed: June 26, 1997
    Date of Patent: August 29, 2000
    Assignees: The Regents of the University of California, Whittier Institute for Diabetes and Endocrinology
    Inventors: Fred Levine, Sijian Wang, Gillian M. Beattie, Alberto Hayek
  • Patent number: 5723333
    Abstract: This invention relates to cell lines, particularly mammalian cell lines, established by transforming the cells with vectors, preferably retroviral vectors, containing two or more oncogenes under the control of one or more inducible promoters and/or genetic elements. Also within the scope of the invention are human cell lines with extended in vitro lifespan, transformed by vectors containing one or more oncogenes under the control of one or more, preferably exogenous, inducible promoters and/or genetic elements. The vectors may additionally contain gene(s) encoding for desired gene product(s). Also disclosed are insulin producing human pancreatic cell lines useful for transplantation into human diabetic patients.
    Type: Grant
    Filed: July 31, 1995
    Date of Patent: March 3, 1998
    Assignee: Regents of The University of California
    Inventors: Fred Levine, Sijian Wang, Gillian M. Beattie, Alberto Hayek