Patents by Inventor Sijie Wang

Sijie Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CBX8 chromdomain inhibitors and the uses thereof
    Patent number: 12162955
    Abstract: The present invention relates to series of peptidomimetic compounds selectively targeting CBX8 of polycomb chromobox protein homolog proteins. Pharmaceutical compositions of those compounds and methods of using them in the treatment of diseases involved CBX8 pharmacology, including various cancers and leukemia, by administering therapeutically effective amounts of such compound alone or together with other therapeutics, are within the scope of this disclosure.
    Type: Grant
    Filed: January 31, 2023
    Date of Patent: December 10, 2024
    Assignee: Purdue Research Foundation
    Inventors: Casey J. Krusemark, Emily C. Dykhuizen, Sijie Wang
  • CBX8 CHROMDOMAIN INHIBITORS AND THE USES THEREOF
    Publication number: 20230257421
    Abstract: The present invention relates to series of peptidomimetic compounds selectively targeting CBX8 of polycomb chromobox protein homolog proteins. Pharmaceutical compositions of those compounds and methods of using them in the treatment of diseases involved CBX8 pharmacology, including various cancers and leukemia, by administering therapeutically effective amounts of such compound alone or together with other therapeutics, are within the scope of this disclosure.
    Type: Application
    Filed: January 31, 2023
    Publication date: August 17, 2023
    Inventors: Casey J. Krusemark, Emily C. Dykhuizen, Sijie Wang
  • CBX8 chromdomain inhibitors and the uses thereof
    Patent number: 11566046
    Abstract: The present invention relates to series of peptidomimetic compounds selectively targeting CBX8 of polycomb chromobox protein homolog proteins. Pharmaceutical compositions of those compounds and methods of using them in the treatment of diseases involved CBX8 pharmacology, including various cancers and leukemia, by administering therapeutically effective amounts of such compound alone or together with other therapeutics, are within the scope of this disclosure.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: January 31, 2023
    Assignee: Purdue Research Foundation
    Inventors: Casey J. Krusemark, Emily C. Dykhuizen, Sijie Wang
  • CBX8 CHROMDOMAIN INHIBITORS AND THE USES THEREOF
    Publication number: 20210284691
    Abstract: The present invention relates to series of peptidomimetic compounds selectively targeting CBX8 of polycomb chromobox protein homolog proteins. Pharmaceutical compositions of those compounds and methods of using them in the treatment of diseases involved CBX8 pharmacology, including various cancers and leukemia, by administering therapeutically effective amounts of such compound alone or together with other therapeutics, are within the scope of this disclosure.
    Type: Application
    Filed: May 18, 2021
    Publication date: September 16, 2021
    Applicant: Purdue Research Foundation
    Inventors: Casey J Krusemark, Emily C Dykhuizen, Sijie Wang
  • CBX8 CHROMDOMAIN INHIBITORS AND THE USES THEREOF
    Publication number: 20200385424
    Abstract: The present invention relates to series of peptidomimetic compounds selectively targeting CBX8 of polycomb chromobox protein homolog proteins. Pharmaceutical compositions of those compounds and methods of using them in the treatment of diseases involved CBX8 pharmacology, including various cancers and leukemia, by administering therapeutically effective amounts of such compound alone or together with other therapeutics, are within the scope of this disclosure.
    Type: Application
    Filed: June 5, 2020
    Publication date: December 10, 2020
    Applicant: Purdue Research Foundation
    Inventors: Casey J. Krusemark, Emily C. Dykhuizen, Sijie Wang