Patents by Inventor SIJIN HE

SIJIN HE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Devices and methods for wound-conformal guidance of bioprinter printhead
    Patent number: 11911582
    Abstract: Disclosed herein is an instrument that enables the in situ formation of architected planar biomaterials and tissues by translating a printer head along a deposition surface such as a patient having burn injuries. In handheld embodiments of the instrument, cell-laden biopolymer solutions are perfused through a moving microfabricated printer head and deposited onto a stationary planar surface or a wound. The printer head may be translated via a drive mechanism. A soft deformable roller mitigates further damage to the injured area of skin as it rolls over it and a gimbal mechanism to which the printer head is attached is in contact with the injured tissue but is configured so that the printer head while in contact with tissue, does not exert undue pressure on the would area.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: February 27, 2024
    Assignees: SUNNYBROOK RESEARCH INSTITUTE, THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Richard Cheng, Gertraud Eylert, Sijin He, Jean-Michel Gariépy, Navid Hakimi, Marc G. Jeschke, Axel Guenther
  • DEVICES AND METHODS FOR WOUND-CONFORMAL GUIDANCE OF BIOPRINTER PRINTHEAD
    Publication number: 20200023172
    Abstract: Disclosed herein is an instrument that enables the in situ formation of architected planar biomaterials and tissues by translating a printer head along a deposition surface such as a patient having burn injuries. In handheld embodiments of the instrument, cell-laden biopolymer solutions are perfused through a moving microfabricated printer head and deposited onto a stationary planar surface or a wound. The printer head may be translated via a drive mechanism. A soft deformable roller mitigates further damage to the injured area of skin as it rolls over it and a gimbal mechanism to which the printer head is attached is in contact with the injured tissue but is configured so that the printer head while in contact with tissue, does not exert undue pressure on the would area.
    Type: Application
    Filed: July 19, 2019
    Publication date: January 23, 2020
    Inventors: RICHARD CHENG, GERTRAUD EYLERT, SIJIN HE, JEAN-MICHEL GARIÉPY, NAVID HAKIMI, MARC G. JESCHKE, AXEL GUENTHER