Abstract: A COMBO ONU optical module circuit is provided, including a MCU control circuit, a XGSPON ONU circuit, and a GPON ONU circuit. The MCU control circuit includes three control units. The first control unit is configured to determine a transmission channel according to a signal level. The second control unit is configured to switch between a TX_SD_10G signal and a TX_SD_1G signal. The third control unit is configured to supply power to the GPONG ONU circuit using PWR_1G control or the XGSPONG ONU circuit using PWR_10G control. The first control unit is further configured to control the XGSPON ONU circuit and the GPON ONU circuit in an I2C communication mode. Under control of the first control unit, the XGSPON ONU circuit is configured to receive and emit a 10G optical signal, and the GPON ONU circuit is configured to receive and emit a2.5G optical signal.

Abstract: The invention discloses a composition and kit for early detection of high-grade cervical lesions and cervical cancer, wherein the composition for early detection of high-grade cervical lesions and cervical cancer includes methylation primers, a probe corresponding to methylated sites and methylation blocking primers for FAM19A4 gene; methylation primers, a probe corresponding to methylated sites and methylation blocking primers for JAM3 gene; methylation primers, a probe corresponding to methylated sites and methylation blocking primers for PAX1 gene; and 1 pair of primers and a probe corresponding to methylated sites for internal reference gene GAPDH.

Abstract: The invention discloses a composition and kit for early detection of high-grade cervical lesions and cervical cancer, wherein the composition for early detection of high-grade cervical lesions and cervical cancer includes methylation primers, a probe corresponding to methylated sites and methylation blocking primers for FAM19A4 gene; methylation primers, a probe corresponding to methylated sites and methylation blocking primers for JAM3 gene; methylation primers, a probe corresponding to methylated sites and methylation blocking primers for PAX1 gene; and 1 pair of primers and a probe corresponding to methylated sites for internal reference gene GAPDH.

Abstract: The present invention discloses markers, primers, probes and a kit for early screening and diagnosis of endometrial cancer. The markers are partial methylated regions in the four genes of CDO1, CELF4, HAND2 and HS3ST2. Detection primers and probes are designed for these methylated regions and to have clasp structures. The kit includes the aforementioned primers and probes. The present invention screens and combines multiple methylated regions to determine the most suitable methylated position for combined diagnosis, which can significantly improve the sensitivity and specificity of the detection for early endometrial cancer. The kit is especially suitable for early screening and diagnosis of endometrial cancer with cervical exfoliated cells as a sample. Even if the DNA template concentration is low, endometrial cancer can be detected. The kit has the advantages of non-invasive sampling, fast detection speed, higher sensitivity and specificity, etc.

Abstract: A electric toothbrush comprises a handle and a brush head. A motor is arranged in the handle and a transmission rod is arranged in the brush head. The motor has a rotating shaft, which extends from a casing of the motor. A transmission connection member is arranged between the transmission rod and the rotating shaft of the motor, one end of the transmission connection member is connected with the rotating shaft, the other end is connected with the transmission rod. A sealing member surrounding the rotating shaft is arranged at the rotating shaft extending position of the outer surface of the casing. The sealing member extends from the outer surface of the casing of the motor to the transmission connection member, and a gap between the inside of the sealing member and the rotating shaft constitutes a first cavity. A second cavity is formed between the sealing member and a sleeving cavity of the transmission connection member.

Abstract: A electric toothbrush comprises a handle and a brush head. A motor is arranged in the handle and a transmission rod is arranged in the brush head. The motor has a rotating shaft, which extends from a casing of the motor. A transmission connection member is arranged between the transmission rod and the rotating shaft of the motor, one end of the transmission connection member is connected with the rotating shaft, the other end is connected with the transmission rod. A sealing member surrounding the rotating shaft is arranged at the rotating shaft extending position of the outer surface of the casing. The sealing member extends from the outer surface of the casing of the motor to the transmission connection member, and a gap between the inside of the sealing member and the rotating shaft constitutes a first cavity. A second cavity is formed between the sealing member and a sleeving cavity of the transmission connection member.