Patents by Inventor Silke BRILL

Silke BRILL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR DETERMINING MUTATIONS FOR INCREASING MODIFIED REPLICABLE RNA FUNCTION AND RELATED COMPOSITIONS AND THEIR USE
    Publication number: 20250250626
    Abstract: The present invention relates to methods for restoring or improving the ability of a modified nucleotide-containing replicable RNA to be replicated and/or translated. The method includes identifying nucleotide changes in the replicable RNA that compensate for the lowered ability of modified-nucleotide-containing replicable RNA molecules to replicate and/or be translated. The present invention also relates to modified nucleotide-containing replicable RNA molecules incorporating such identified nucleotide changes and the use of such replicable RNA molecules in therapy.
    Type: Application
    Filed: October 17, 2022
    Publication date: August 7, 2025
    Inventors: Tim BEISSERT, Mario PERKOVIC, Stefanie GAWLETTA, Patrick SORN, Silke BRILL, Evelin NETT
  • MATERIALS AND METHODS FOR CELL CULTURE
    Publication number: 20150329826
    Abstract: Methods and compositions for improved cell growth and serum-reduced or -free cell culture media.
    Type: Application
    Filed: December 12, 2013
    Publication date: November 19, 2015
    Inventors: Christian VAN DEN BOS, Alexis BOSSIE, Silke BRILL, Agnieszka SAFAVI-NAB, Frank JUENGERKES, Barbara REINISCH, Claudia ROSENBAUM, Judith SCHENK