Patents by Inventor Silke Dlugai

Silke Dlugai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • yeast strain with functional expression of a GLUT transporter gene
    Patent number: 8574909
    Abstract: The invention relates to a strain of the yeast Saccharomyces cerevisiae which, owing to deletion of the genomic sequences, no longer synthesizes hexose transporters and, as a consequence, can no longer grow on substrates with hexoses as the only carbon source, and whose ability of growing on a substrate with a hexose as the only carbon source is restored when it expresses a GLUT4 gene.
    Type: Grant
    Filed: April 7, 2006
    Date of Patent: November 5, 2013
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Guenter Mueller, Klaus-Peter Koller, Eckhard Boles, Roman Niedbal, Silke Dlugai
  • Use of mutants for expressing mammalian glucose transporters
    Patent number: 8298812
    Abstract: The invention relates to yeast strains in which a human GLUT4 transport or a human GLUT1 transporter can be functionally expressed and to particular GLUT4 transport proteins which can be functionally expressed particularly readily in yeast strains.
    Type: Grant
    Filed: November 9, 2009
    Date of Patent: October 30, 2012
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Guenter Mueller, Silke Dlugai, Doerthe Voss, Eckhard Boles
  • USE OF SACCHAROMYCES CEREVISIAE ERG4 MUTANTS FOR EXPRESSING MAMMALIAN GLUCOSE TRANSPORTERS
    Publication number: 20100203617
    Abstract: The invention relates to yeast strains in which a human GLUT4 transport or a human GLUT1 transporter can be functionally expressed and to particular GLUT4 transport proteins which can be functionally expressed particularly readily in yeast strains.
    Type: Application
    Filed: November 9, 2009
    Publication date: August 12, 2010
    Applicant: SANOFI AVENTIS DEUTSCHLAND GMBH
    Inventors: Guenter MUELLER, Silke DLUGAI, Doerthe VOSS, Eckhard BOLES
  • Use of mutants for expressing mammalian glucose transporter
    Patent number: 7615360
    Abstract: The invention relates to yeast strains in which a human GLUT4 transport or a human GLUT1 transporter can be functionally expressed and to particular GLUT4 transport proteins which can be functionally expressed particularly readily in yeast strains.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: November 10, 2009
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Guenter Mueller, Silke Dlugai, Doerthe Voss, Eckhard Boles
  • THE USE OF SACCHAROMYCES CEREVISIAE ERG4 MUTANTS FOR EXPRESSING MAMMALIAN GLUCOSE TRANSPORTER
    Publication number: 20080020419
    Abstract: The invention relates to yeast strains in which a human GLUT4 transport or a human GLUT1 transporter can be functionally expressed and to particular GLUT4 transport proteins which can be functionally expressed particularly readily in yeast strains.
    Type: Application
    Filed: July 10, 2007
    Publication date: January 24, 2008
    Applicant: SANOFI AVENTIS DEUTSCHLAND GMBH
    Inventors: Guenter Mueller, Silke Dlugai, Doerthe Voss, Eckhard Boles
  • Use of erg4 mutants for expressing mammalian glucose transporters
    Patent number: 7244821
    Abstract: The invention relates to yeast strains in which a human GLUT4 transport or a human GLUT1 transporter can be functionally expressed and to particular GLUT4 transport proteins which can be functionally expressed particularly readily in yeast strains.
    Type: Grant
    Filed: September 10, 2003
    Date of Patent: July 17, 2007
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Guenter Mueller, Silke Dlugai, Doerthe Voss, Eckhard Boles
  • Saccharomyces cerevisiae yeast strain with functional expression of a GLUT transporter
    Publication number: 20060275319
    Abstract: The invention relates to a strain of the yeast Saccharomyces cerevisiae which, owing to deletion of the genomic sequences, no longer synthesizes hexose transporters and, as a consequence, can no longer grow on substrates with hexoses as the only carbon source, and whose ability of growing on a substrate with a hexose as the only carbon source is restored when it expresses a GLUT4 gene.
    Type: Application
    Filed: April 7, 2006
    Publication date: December 7, 2006
    Applicant: sanofi-aventis Deutschland GmbH
    Inventors: Gunter Muller, Klaus-Peter Koller, Eckhard Boles, Roman Wieczorke, Silke Dlugai
  • yeast strain with functional expression of a Glut transporter
    Patent number: 7052900
    Abstract: The invention relates to a strain of the yeast Saccharomyces cerevisiae which, owing to deletion of the genomic sequences, no longer synthesizes hexose transporters and, as a consequence, can no longer grow on substrates with hexoses as the only carbon source, and whose ability of growing on a substrate with a hexose as the only carbon source is restored when it expresses a GLUT4 gene.
    Type: Grant
    Filed: February 5, 2002
    Date of Patent: May 30, 2006
    Assignee: sanofi-aventis Pharma Deutschland GmbH
    Inventors: Gunter Muller, Klaus-Peter Koller, Eckhard Boles, Roman Wieczorke, Silke Dlugai
  • Use of Saccharomyces cerevisiae Erg4 mutants for expressing mammalian glucose transporters
    Publication number: 20050074845
    Abstract: The invention relates to yeast strains in which a human GLUT4 transport or a human GLUT1 transporter can be functionally expressed and to particular GLUT4 transport proteins which can be functionally expressed particularly readily in yeast strains.
    Type: Application
    Filed: September 10, 2003
    Publication date: April 7, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Guenter Mueller, Silke Dlugai, Doerthe Voss, Eckhard Boles
  • Saccharomyces cerevisiae yeast strain with functional expression of a glut transporter
    Publication number: 20030166258
    Abstract: The invention relates to a strain of the yeast Saccharomyces cerevisiae which, owing to deletion of the genomic sequences, no longer synthesizes hexose transporters and, as a consequence, can no longer grow on substrates with hexoses as the only carbon source, and whose ability of growing on a substrate with a hexose as the only carbon source is restored when it expresses a GLUT4 gene.
    Type: Application
    Filed: February 5, 2002
    Publication date: September 4, 2003
    Inventors: Gunter Muller, Klaus-Peter Koller, Eckhard Boles, Roman Wieczorke, Silke Dlugai