Patents by Inventor Silva Rodriquez

Silva Rodriquez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleotide sequence coding for an outer membrane protein from Neisseria meningitidis and use of said protein in vaccine preparations
    Patent number: 5286484
    Abstract: The present invention is concerned with a method for the isolation of a nucleotide sequence which codes for a protein having a molecular weight of about 64,000 daltons, which is located on the outer membrane of N. meningitidis, as well as with the recombinant DNA obtained therefrom, which is used for the transformation of a host microorganism. The technical object pursued with the invention is the identification of a nucleotide sequence coding for a highly conserved and common protein for the majority of pathogenic Neisseria strains, the production of this protein with a high level of purity and in commercially useful amounts using the recombinant way, so that it can be used in diagnostic methods and vaccine preparations with a broad immunoprotection spectrum.
    Type: Grant
    Filed: September 5, 1991
    Date of Patent: February 15, 1994
    Assignee: Centro de Ingenieria Genetica y Biotecnologia
    Inventors: Silva Rodriquez, Selman H. Sosa, Guillen Nieto, Saturnino H. Martinez, Julio R. F. Maso, Lidia I. N. Perez, Juan M. Grillo, Vivian M. Cordova, Sonia G. Blanco, Beatriz T. Santos, Jesus A. del Valle Rosales, Evelin C. Menendez, Anabel A. Acosta, Edelgis C. Rodriquez, Silian C. Leon, Alexis M. Lasa