Patents by Inventor Silvana Leit

Silvana Leit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of Histone Deacetylase
    Publication number: 20080132459
    Abstract: The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
    Type: Application
    Filed: September 24, 2004
    Publication date: June 5, 2008
    Applicant: MethylGene, Inc.
    Inventors: Oscar Moradei, Isabelle Paquin, Silvana Leit, Sylvie Frechette, Arkadii Vaisburg, Jeffrey M. Besterman, Pierre Tessier, Tammy C. Mallais
  • SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS
    Publication number: 20070293530
    Abstract: This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula (I), and racemic and scalemic mixtures, diastereomers and enantiomers thereof: or an N-oxide, hydrate, solvate, pharmaceutically acceptable salt, prodrug or complex thereof, wherein Y, L, Z, W, M, Ra, Rb and Rc are as defined in the specification.
    Type: Application
    Filed: June 14, 2007
    Publication date: December 20, 2007
    Applicant: METHYLGENE INC.
    Inventors: David Smil, Silvana Leit, Alain Ajamian, Martin Allan, Yves Chantigny, Robert Deziel, Eric Therrien, Amal Wahhab, Sukhdev Manku
  • Inhibitors of Histone Deacetylase
    Publication number: 20070213330
    Abstract: The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
    Type: Application
    Filed: March 16, 2007
    Publication date: September 13, 2007
    Applicant: METHYLGENE INC.
    Inventors: Daniel Delorme, Arkadii Vaisburg, Oscar Moradei, Silvana Leit, Stephane Raeppel, Sylvie Frechette, Giliane Bouchain, Zhihong Zhou, Isabelle Paquin, Frederic Gaudette, Ljubomir Isakovic
  • Inhibitors of histone deacetylase
    Patent number: 7253204
    Abstract: The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
    Type: Grant
    Filed: March 25, 2005
    Date of Patent: August 7, 2007
    Assignee: MethylGene Inc.
    Inventors: Daniel Delorme, Arkadii Vaisburg, Oscar Moradei, Silvana Leit, Stephane Raeppel, Sylvie Frechette, Giliane Bouchain, Zhihong Zhou, Isabelle Paquin, Frederic Gaudette, Ljubomir Isakovic
  • Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase
    Publication number: 20070155730
    Abstract: This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula (I) wherein A, B, D, E, X1, X2, X3, X4 and n are as defined in the specification.
    Type: Application
    Filed: August 25, 2006
    Publication date: July 5, 2007
    Applicant: METHYLGENE, INC.
    Inventors: Silvana Leit, Amal Wahhab, Martin Allan, David Smil, Pierre Tessier, Robert Deziel, Yves Chantigny
  • Inhibitors of histone deacetylase
    Publication number: 20060264415
    Abstract: This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula (I) wherein Y, L, Z, W, X, Q, R1, R2 and R3 are as defined in the specification.
    Type: Application
    Filed: March 31, 2006
    Publication date: November 23, 2006
    Inventors: Silvana Leit de Moradei, Pierre Tessier, David Smil, Amal Wahhab, Robert Deziel, Sukhdev Manku, John Mancuso, Eric Therrien, Martin Allan, Yves Chantigny, Alain Ajamian, Patrick Beaulieu
  • Inhibitors of histone deacetylase
    Publication number: 20060058298
    Abstract: The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
    Type: Application
    Filed: March 15, 2005
    Publication date: March 16, 2006
    Inventors: Daniel Delorme, Soon Woo, Arkadii Vaisburg, Oscar Moradei, Silvana Leit, Stephane Raeppel, Sylvie Frechette, Giliane Bouchain
  • Inhibitors of histone deacetylase
    Publication number: 20050288282
    Abstract: The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
    Type: Application
    Filed: March 25, 2005
    Publication date: December 29, 2005
    Inventors: Daniel Delorme, Soon Hyung Woo, Arkadii Vaisburg, Oscar Moradei, Silvana Leit, Stephane Raeppel, Sylvie Frechette, Giliane Bouchain
  • Inhibitors of histone deacetylase
    Publication number: 20050245518
    Abstract: The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
    Type: Application
    Filed: March 25, 2005
    Publication date: November 3, 2005
    Inventors: Daniel Delorme, Arkadii Vaisburg, Oscar Moradei, Silvana Leit, Stephane Raeppel, Sylvie Frechette, Giliane Bouchain, Zhihong Zhou, Isabelle Paquin, Frederic Gaudette, Ljubomir Isakovic
  • Inhibitors of histone deacetylase
    Publication number: 20040106599
    Abstract: The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
    Type: Application
    Filed: September 12, 2002
    Publication date: June 3, 2004
    Inventors: Daniel Delorme, Soon Hyung Woo, Arkadii Vaisburg, Oscar Moradei, Silvana Leit, Stephane Raeppel, Sylvie Frechette, Giliane Bouchain