Patents by Inventor Silvana Marcel Leit de Moradei

Silvana Marcel Leit de Moradei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CBL-B MODULATORS AND USES THEREOF
    Publication number: 20230086064
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of Cbl-b, and the treatment of Cbl-b-mediated disorders.
    Type: Application
    Filed: April 8, 2022
    Publication date: March 23, 2023
    Inventors: Silvana Marcel LEIT DE MORADEI, Angela V. WEST, Thomas BAKER, Jokin Carrillo ARREGUI, Diana CASTAGNA, Jeremy Robert GREENWOOD, Salma RAFI, Fiona MCROBB, Yan ZHANG
  • ACLY inhibitors and uses thereof
    Patent number: 11555012
    Abstract: The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: January 17, 2023
    Assignee: Nimbus Artemis, Inc.
    Inventors: Silvana Marcel Leit de Moradei, Eric Therrien
  • ACLY inhibitors and uses thereof
    Patent number: 11492341
    Abstract: The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: November 8, 2022
    Assignee: Nimbus Artemis, Inc.
    Inventors: Silvana Marcel Leit de Moradei, Kevin Kreutter, H. James Harwood, Eric Therrien
  • TYK2 inhibitors and uses thereof
    Patent number: 11396508
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: July 26, 2022
    Assignee: Nimbus Lakshmi, Inc.
    Inventors: Jeremy Robert Greenwood, Silvana Marcel Leit de Moradei, Craig E. Masse, Thomas H. McLean, Sayan Mondal
  • TYK2 inhibitors and uses thereof
    Patent number: 11220508
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: January 11, 2022
    Assignee: Nimbus Lakshmi, Inc.
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit De Moradei, Craig E. Masse, Thomas H. McLean, Sayan Mondal
  • TYK2 inhibitors and uses thereof
    Patent number: 11174265
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: November 16, 2021
    Assignee: Nimbus Lakshmi, Inc.
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit De Moradei, Craig E. Masse, Thomas H. McLean, Sayan Mondal
  • Ester ACC inhibitors and uses thereof
    Patent number: 11098055
    Abstract: The present invention provides ester compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: August 24, 2021
    Assignee: Gilead Apollo, LLC
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit De Moradei
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20210230163
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: May 4, 2020
    Publication date: July 29, 2021
    Inventors: Jeremy Robert GREENWOOD, Geraldine C. HARRIMAN, Silvana Marcel LEIT DE MORADEI, Craig E. MASSE, Thomas H. MCLEAN, Sayan MONDAL
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20210094948
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: February 28, 2020
    Publication date: April 1, 2021
    Inventors: Jeremy Robert Greenwood, Silvana Marcel Leit de Moradei, Craig E. Masse, Thomas H. McLean, Sayan Mondal
  • Pesticidal compositions and uses thereof
    Patent number: 10941157
    Abstract: Provided herein are compounds that exhibit activity as fungicides and are useful, for example, in methods for the control of fungal pathogens in plants and can be applied to said plants in a variety of ways.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: March 9, 2021
    Assignee: Gilead Apollo, LLC
    Inventors: Jennifer Lynn Bennett, Karen C. Fitzsimmons, Shomir Ghosh, Jeremy Robert Greenwood, William P. Haakenson, Jr., Geraldine C. Harriman, Silvana Marcel Leit De Moradei, Barry J. Shortt, Urszula J. Slomczynska, Jeffrey Michael Stein
  • Pyrazole ACC inhibitors and uses thereof
    Patent number: 10941158
    Abstract: The present invention provides pyrazole compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: March 9, 2021
    Assignee: Gilead Apollo, LLC
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei
  • Triazole ACC inhibitors and uses thereof
    Patent number: 10800791
    Abstract: The present invention provides triazole compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: October 13, 2020
    Assignee: Gilead Apollo, LLC
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit De Moradei
  • TYK2 inhibitors and uses thereof
    Patent number: 10793574
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: October 6, 2020
    Assignee: Nimbus Lakshmi, Inc.
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei, Craig E. Masse, Thomas H. McLean, Sayan Mondal
  • ACLY INHIBITORS AND USES THEREOF
    Publication number: 20200157076
    Abstract: The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.
    Type: Application
    Filed: November 15, 2019
    Publication date: May 21, 2020
    Inventors: Silvana Marcel Leit de Moradei, Kevin Kreutter, H. James Harwood, Eric Therrien
  • ACLY INHIBITORS AND USES THEREOF
    Publication number: 20200148634
    Abstract: The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.
    Type: Application
    Filed: November 8, 2019
    Publication date: May 14, 2020
    Inventors: Silvana Marcel Leit de Moradei, Eric Therrien
  • TYK2 inhibitors and uses thereof
    Patent number: 10647713
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: May 12, 2020
    Assignee: Nimbus Lakshmi, Inc.
    Inventors: Jeremy Robert Greenwood, Silvana Marcel Leit de Moradei, Craig E. Masse, Thomas H. McLean, Sayan Mondal
  • TRIAZOLE ACC INHIBITORS AND USES THEREOF
    Publication number: 20200017519
    Abstract: The present invention provides triazole compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: April 24, 2019
    Publication date: January 16, 2020
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit De Moradei
  • ESTER ACC INHIBITORS AND USES THEREOF
    Publication number: 20200010478
    Abstract: The present invention provides ester compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: January 24, 2019
    Publication date: January 9, 2020
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit De Moradei
  • PYRAZOLE ACC INHIBITORS AND USES THEREOF
    Publication number: 20190375759
    Abstract: The present invention provides pyrazole compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: January 3, 2019
    Publication date: December 12, 2019
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei
  • ACC INHIBITORS AND USES THEREOF
    Publication number: 20190330224
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: November 27, 2018
    Publication date: October 31, 2019
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei