Abstract: Disclosed is a device for simulating the movement of an endoscope in an environment, including: a tube modelling an endoscope tube; and a tracking module including a housing into which the tube is insertable and movable. The tracking module includes a detector of movements of the tube in the housing and a unit for communicating the detected movements to a controller. The controller is configured to generate, at each instant, an image of a portion of an environment based on the movements of the tube detected by the detector so as to simulate the movement of an endoscope in the environment. The tracking module includes a fastener adapted to fasten the tracking module in a releasable manner onto a support.

Abstract: The invention relates to a hybrid hydrogel, in particular degradable or non-degradable, comprising a first hydrogel polymer of formula (I) in association with an alginate hydrogel polymer, and optionally organosilica particles in particular degradable or non-degradable nanoparticles, or porous silicon particles; pharmaceutical, veterinary and/or cosmetic compositions thereof; and uses thereof as a medicament. The invention notably relates to the use of such hybrid hydrogel in the treatment of fistulas and physiological leaks/leakages, notably in the gastrointestinal tract. The present invention finds applications in the therapeutic and diagnostic medical technical fields and also in cosmetic and veterinary technical fields.

Abstract: The invention relates to a hydrogel, in particular degradable or non degradable, comprising monomers of formula (I) and organosilica particles or porous silicon particles covalently bound thereto, optionally with non covalently bound organosilica and/or silicon particles mixed therewith, in particular degradable organosilica nanoparticles or core-shell nanocapsules; pharmaceutical, veterinary or cosmetic compositions thereof; and uses thereof as a medicament. The present invention finds applications in the therapeutic and diagnostic medical technical fields and also in cosmetic and veterinary technical fields.

Abstract: Provided herein is a clip for organ retraction or organ exposure during minimal invasive surgery wherein the clip comprises a body made of a biocompatible material wherein the body comprises at least two generally opposing first and second segments that form a jaw defined by a separation between the two segments; wherein the two segments each comprise distal and proximal ends wherein the proximal ends may be directly connected or connected through one or more segments within the body of the clip and wherein the clip defines at least four configurations a resting configuration, an open configuration, a grabbing configuration, and a sliding configuration.

Abstract: An endoscopic instrument system for performing endoscopic interventions via a natural access path, including a flexible endoscope with an endoscope handle and an elongate endoscope shaft introducible into a hollow space in a body, wherein the endoscope shaft includes a steerable end section and at least one instrument channel, and also includes an endoscopic instrument with a handle, an elongate instrument shaft and a tool which can be actuated by a pull and/or push element arranged within the instrument shaft and connected to the handle and to the tool, wherein the endoscopic instrument can be introduced into the instrument channel for conducting manipulations in the hollow space in the body, and wherein the instrument shaft includes a continuous flexible tube that is connected, such that it is rotationally fixed, to the handle and to the tool with respect to a longitudinal direction of the tube.

Abstract: Provided herein is a clip for organ retraction or organ exposure during minimal invasive surgery wherein the clip comprises a body made of a biocompatible material wherein the body comprises at least two generally opposing first and second segments that form a jaw defined by a separation between the two segments; wherein the two segments each comprise distal and proximal ends wherein the proximal ends may be directly connected or connected through one or more segments within the body of the clip and wherein the clip defines at least four configurations a resting configuration, an open configuration, a grabbing configuration, and a sliding configuration.

Abstract: An endoscopic instrument system for performing endoscopic interventions via a natural access path, including a flexible endoscope with an endoscope handle and an elongate endoscope shaft introducible into a hollow space in a body, wherein the endoscope shaft includes a steerable end section and at least one instrument channel, and also includes an endoscopic instrument with a handle, an elongate instrument shaft and a tool which can be actuated by a pull and/or push element arranged within the instrument shaft and connected to the handle and to the tool, wherein the endoscopic instrument can be introduced into the instrument channel for conducting manipulations in the hollow space in the body, and wherein the instrument shaft includes a continuous flexible tube that is connected, such that it is rotationally fixed, to the handle and to the tool with respect to a longitudinal direction of the tube.