Patents by Inventor Silvana Rensina Antonnietta Di Silvestre

Silvana Rensina Antonnietta Di Silvestre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10434071
    Abstract: The present invention relates to a drug delivery system comprising a core and a shell in which the core comprises a hydrolytically degradable polymer X which polymer backbone comprises pendant ester and acid functionalities and in which the shell comprises a hydrolytic degradable polymer Y. The hydrolytic degradable polymers X and Y are different polymers. Polymer X further comprises amino-acids in the polymer backbone and degrades via zero order degradation kinetics for a period of at least 3 months. Polymer Y degrades via auto-acceleration degradation kinetics.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: October 8, 2019
    Assignee: DSM IP ASSETS, B.V.
    Inventors: George Mihov, Guy Draaisma, Silvana Rensina Antonnietta Di Silvestre, Tristan Handels
  • Publication number: 20170367992
    Abstract: The present invention relates to a drug delivery system comprising a core and a shell in which the core comprises a hydrolytically degradable polymer X which polymer backbone comprises pendant ester and acid functionalities and in which the shell comprises a hydrolytic degradable polymer Y. The hydrolytic degradable polymers X and Y are different polymers. Polymer X further comprises amino-acids in the polymer backbone and degrades via zero order degradation kinetics for a period of at least 3 months. Polymer Y degrades via auto-acceleration degradation kinetics.
    Type: Application
    Filed: December 18, 2015
    Publication date: December 28, 2017
    Inventors: George MIHOV, Guy DRAAISMA, Silvana Rensina Antonnietta DI SILVESTRE, Tristan HANDELS
  • Publication number: 20140309378
    Abstract: This invention relates to an unsaturated polyester resin composition characterized in that the resin composition comprises a. An unsaturated polyester resin comprising fumaric, maleic and/or itaconic building blocks, b. At least one vinyl ester as reactive diluent, c. An iron complex and/or salt, and d.
    Type: Application
    Filed: December 5, 2012
    Publication date: October 16, 2014
    Inventors: Johan Franz Gradus Antonius Jansen, Iris Hilker, Guido Joseph Elisabeth Hensen, Silvana Rensina Antonnietta Di Silvestre
  • Patent number: 8790762
    Abstract: The present invention relates to an unsaturated polyester resin comprising itaconate esters as reactive unsaturations, wherein the acid value of the resin is in the range of from 25 to 125 and the molar ratio of hydroxyl end groups and carboxylic acid end groups is in the range of from 0.33 to 3. In one embodiment, the molar ratio of hydroxyl end groups and carboxylic acid end groups is in the range of from 0.33 to 0.9. In another embodiment, the molar ratio of hydroxyl end groups and carboxylic acid end groups is in the range of from 1.1 to 3.
    Type: Grant
    Filed: March 24, 2010
    Date of Patent: July 29, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Marian Henryk Szkudlarek, Johan Franz Gradus Antonius Jansen, Silvana Rensina Antonnietta Di Silvestre, Stefanus Jacobus Duyvestijn
  • Patent number: 8470926
    Abstract: The present invention relates to an unsaturated polyester resin comprising itaconate ester units as reactive unsaturation, wherein the resin comprises itaconate, citraconate and mesaconate ester units. Preferably, the resin comprises itaconate, citraconate and mesaconate ester units in an amount of from 40 to 90 mol % itaconate, from 2 to 30 mol % citraconate and from 5 to 40 mol % mesaconate in which 100 mol % is the total amount of itaconate, citraconate and mesaconate esters units.
    Type: Grant
    Filed: March 24, 2010
    Date of Patent: June 25, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Marian Henryk Szkudlarek, Johan Franz Gradus Antonius Jansen, Stefanus Jacobus Duyvestijn, Silvana Rensina Antonnietta Di Silvestre
  • Publication number: 20120121841
    Abstract: The present invention relates to an unsaturated polyester resin comprising itaconate esters as reactive unsaturations, wherein the acid value of the resin is in the range of from 25 to 125 and the molar ratio of hydroxyl end groups and carboxylic acid end groups is in the range of from 0.33 to 3. In one embodiment, the molar ratio of hydroxyl end groups and carboxylic acid end groups is in the range of from 0.33 to 0.9. In another embodiment, the molar ratio of hydroxyl end groups and carboxylic acid end groups is in the range of from 1.1 to 3.
    Type: Application
    Filed: March 24, 2010
    Publication date: May 17, 2012
    Applicant: DSM IP Assets B.V.
    Inventors: Marian Henryk Szkudlarek, Johan Franz Gradus Antonius Jansen, Silvana Rensina Antonnietta Di Silvestre, Stefanus Jacobus Duyvestijn
  • Publication number: 20120095160
    Abstract: The present invention relates to an unsaturated polyester resin comprising itaconate ester units as reactive unsaturation, wherein the resin comprises itaconate, citraconate and mesaconate ester units. Preferably, the resin comprises itaconate, citraconate and mesaconate ester units in an amount of from 40 to 90 mol % itaconate, from 2 to 30 mol % citraconate and from 5 to 40 mol % mesaconate in which 100 mol % is the total amount of itaconate, citraconate and mesaconate esters units.
    Type: Application
    Filed: March 24, 2010
    Publication date: April 19, 2012
    Inventors: Marian Henryk Szkudlarek, Johan Franz Gradus Antonnius Jansen, Stefanus Jacobus Duyvestijn, Silvana Rensina Antonnietta Di Silvestre