Patents by Inventor Silvia A. Mandel

Silvia A. Mandel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination of Deuterated Levodopa With Carbidopa and Opicapone For The Treatment of Parkinson's Disease
    Publication number: 20200121812
    Abstract: The present invention relates to new combinations of treatments for abnormal dopamine deficiency disorders, and related conditions, comprising deuterated catecholamine derivatives and catechol-O-methyltransferase (COMT) inhibitors.
    Type: Application
    Filed: August 29, 2019
    Publication date: April 23, 2020
    Inventors: Hermann Russ, Silvia A. Mandel, Aric Orbach
  • Combination of Deuterated Levodopa With Carbidopa and Opicapone For The Treatment of Parkinson's Disease
    Publication number: 20170165381
    Abstract: The present invention relates to new combinations of treatments for abnormal dopamine deficiency disorders, and related conditions, comprising deuterated catecholamine derivatives and catechol-O-methyltransferase (COMT) inhibitors.
    Type: Application
    Filed: January 9, 2017
    Publication date: June 15, 2017
    Inventors: Hermann Russ, Silvia A. Mandel, Aric Orbach
  • DIAGNOSTIC TEST FOR PARKINSON'S DISEASE
    Publication number: 20100221735
    Abstract: The present invention relates to molecular markers for detection, prognosis and follow up of Parkinson's disease (PD), wherein said molecular markers are one or more genes with altered expression pattern, or gene products thereof (RNA or protein). Genes which expression is upregulated or downregulated in PD patients are tools for early diagnosis od PD, for monitoring the progress of the disease and can serve as targets for screening new agents for treatment of PD.
    Type: Application
    Filed: March 3, 2010
    Publication date: September 2, 2010
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Moussa B.H. YOUDIM, Silvia A. Mandel, Edna Grünblatt, Peter Riederer