Patents by Inventor Silvia Andrade

Silvia Andrade has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions of semicarbazones and/or thiosemicarbazones and/or their derivatives and products of these compositions and their uses as anticonvulsant, anti-nociceptive and anti-inflammatory agents, and in the angiogenic therapy
    Publication number: 20080058284
    Abstract: The present invention is characterized by obtaining inclusion compounds of semicarbazones and/or thiosemicarbazones and/or their derivatives in cyclodextrins and/or their derivatives, which once tested in experimental models of epilepsia allowed the reduction of anticonvulsant dose from 100 mg/kg to 25 mg/kg. This means an increase in bioavailability of compounds in biological systems. Hence inclusion compounds between semicarbazones and/or thiosemicarbazones and cyclodextrins and their derivatives could be new candidates as anticonvulsant agents. The present invention is also characterized by the increase in the anticonvulsant efficacy of the inclusion compounds between cyclodextrins and/or their derivatives and semicarbazones and/or thiosemicarbazones and/or their derivatives in comparison to free components.
    Type: Application
    Filed: July 30, 2007
    Publication date: March 6, 2008
    Applicant: UNIVERSIDALE FEDERAL DE MINAS GERAIS
    Inventors: Ruben Millan, Marcio Coelho, Rafael Vieira, Letica Teixeira, Maria Doreto, Heloisa Beraldo, Silvia Andrade