Patents by Inventor Silvia GALBIATI

Silvia GALBIATI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11230732
    Abstract: An assay for detecting gene fragments, including: amplifying gene fragments comprising single-nucleotide polymorphisms (SNPs) to form an initial amplification product; isolating single strand oligonucleotides of interest from the initial amplification product; forming a solution comprising the oligonucleotides of interest and reporter molecules, each reporter molecule having a first oligonucleotide domain configured to hybridize with a complementary oligonucleotide of interest, and a second oligonucleotide domain configured to hybridize with a complementary capture probe; hybridizing, in the solution, the oligonucleotides of interest with the reporter molecules that have complementary first domains; applying the solution to the surface of a microarray including an array of capture probes fixed to a microarray slide; capturing the oligonucleotides of interest on the microarray by hybridizing the second oligonucleotide domains of the reporter molecules with complementary capture probes of the microarray; and de
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: January 25, 2022
    Inventors: Marcella Chiari, Francesco Damin, Silvia Galbiati, Maurizio Ferrari
  • Publication number: 20200102605
    Abstract: An assay method for a gene fragment of interest comprising: amplify at least one gene fragment of interest comprising or potentially comprising at least one SNP region of interest to form an initial amplification product; forming at least one single strand amplification product from the initial amplification product, wherein the single strand amplification product either comprises or potentially comprises the at least one SNP region of interest; hybridize in solution the single strand amplification product with at least one reporter molecule which comprises at least two, different domains of oligonucleotide, wherein a first domain of oligonucleotide is for hybridization with the single strand amplification product, and wherein the second domain of oligonucleotide is for hybridization to at least one microarray probe surface, wherein the microarray probe surface comprises at least one capture probe to allow for hybridization; contact the solution of the hybridized single strand amplification product with the a
    Type: Application
    Filed: March 30, 2018
    Publication date: April 2, 2020
    Inventors: Marcella CHIARI, Francesco DAMIN, Silvia GALBIATI, Maurizio FERRARI