Patents by Inventor Silvia Pozzi

Silvia Pozzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TDP-43-binding polypeptides useful for the treatment of neurodegenerative diseases
    Patent number: 10202443
    Abstract: Provided herein are antigen-binding constructs such as antibodies that bind to the RRM-1 domain of TDP-43. The antigen-binding constructs are capable of blocking the interaction of TDP-43 with NF-?B in cells. Also provided herein are method of using the antigen-binding constructs in the treatment of diseases associated with TPD-43 proteinopathy, such as amyotrophic lateral sclerosis (ALS), frontotemperal lobar degeneration (FTLD), Lewy body disease and motor neuron disease.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: February 12, 2019
    Assignee: UNIVERSITÉ LAVAL
    Inventors: Jean-Pierre Julien, Claude Gravel, Silvia Pozzi
  • TDP-43-Binding Polypeptides Useful for the Treatment of Neurodegenerative Diseases
    Publication number: 20170355756
    Abstract: Provided herein are antigen-binding constructs such as antibodies that bind to the RRM-1 domain of TDP-43. The antigen-binding constructs are capable of blocking the interaction of TDP-43 with NF-?B in cells. Also provided herein are method of using the antigen-binding constructs in the treatment of diseases associated with TPD-43 proteinopathy, such as amyotrophic lateral sclerosis (ALS), frontotemperal lobar degeneration (FTLD), Lewy body disease and motor neuron disease.
    Type: Application
    Filed: December 7, 2015
    Publication date: December 14, 2017
    Inventors: Jean-Pierre Julien, Claude Gravel, Silvia Pozzi