Patents by Inventor Silvia Ramirez

Silvia Ramirez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250122530
    Abstract: The disclosure provides various compositions comprising novel adeno-associated virus (AAV) capsid sequences and functional fragments thereof. Also provided, are methods of delivery, treatment and manufacture using the compositions provided by the disclosure.
    Type: Application
    Filed: September 2, 2022
    Publication date: April 17, 2025
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Peter COLOSI, Vincent LEONARD, Silvia RAMIREZ, Justin ISHIDA, Yu-Shan TSENG, Teague STERLING
  • Publication number: 20240384242
    Abstract: The disclosure provides various compositions comprising novel adeno-associated virus (AAV) capsid sequences and functional fragments thereof. Also provided, are methods of delivery, treatment and manufacture using the compositions provided by the disclosure.
    Type: Application
    Filed: September 2, 2022
    Publication date: November 21, 2024
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Peter COLOSI, Vincent LEONARD, Silvia RAMIREZ, Justin ISHIDA, Yu-Shan TSENG, Teague STERLING
  • Publication number: 20240376495
    Abstract: The disclosure provides various compositions comprising novel adeno-associated virus (AAV) capsid sequences and functional fragments thereof. Also provided, are methods of delivery, treatment and manufacture using the compositions provided by the disclosure.
    Type: Application
    Filed: September 2, 2022
    Publication date: November 14, 2024
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Peter COLOSI, Vincent LEONARD, Silvia RAMIREZ, Justin ISHIDA, Yu-Shan TSENG, Teague STERLING
  • Publication number: 20240376496
    Abstract: The disclosure provides various compositions comprising novel adeno-associated virus (AAV) capsid sequences and functional fragments thereof. Also provided, are methods of delivery, treatment and manufacture using the compositions provided by the disclosure.
    Type: Application
    Filed: September 2, 2022
    Publication date: November 14, 2024
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Peter COLOSI, Vincent LEONARD, Silvia RAMIREZ, Justin ISHIDA, Yu-Shan TSENG, Teague STERLING
  • Publication number: 20240200096
    Abstract: The present disclosure relates, in general, to methods for readministering, or redosing, a subject having undergone a first gene therapy regimen with a second, or subsequent, administration of a gene therapy regimen, wherein the first gene therapy vector and second gene therapy vector comprise different AAV capsids but carry a transgene or polynucleotide useful to treat the same disease or disorder.
    Type: Application
    Filed: October 2, 2023
    Publication date: June 20, 2024
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Peter COLOSI, Justin ISHIDA, Silvia RAMIREZ
  • Patent number: 11821008
    Abstract: The invention relates to novel adeno-associated virus (AAV) capsid proteins, AAV particles comprising a novel capsid protein, polynucleotides encoding these capsid proteins and AAV vectors expressing these capsid proteins. The invention also relates to methods of making the herein described AAV vectors expressing the novel capsid proteins of the invention and associated therapeutic uses of thereof.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: November 21, 2023
    Assignee: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Peter Cameron Colosi, Silvia Ramirez
  • Publication number: 20200362368
    Abstract: The present disclosure relates, in general, to methods for readministering, or redosing, a subject having undergone a first gene therapy regimen with a second, or subsequent, administration of a gene therapy regimen, wherein the first gene therapy vector and second gene therapy vector comprise different AAV capsids but carry a transgene or polynucleotide useful to treat the same disease or disorder.
    Type: Application
    Filed: May 13, 2020
    Publication date: November 19, 2020
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Peter COLOSI, Justin ISHIDA, Silvia RAMIREZ
  • Publication number: 20200024579
    Abstract: The invention relates to novel adeno-associated virus (AAV) capsid proteins, AAV particles comprising a novel capsid protein, polynucleotides encoding these capsid proteins and AAV vectors expressing these capsid proteins. The invention also relates to methods of making the herein described AAV vectors expressing the novel capsid proteins of the invention and associated therapeutic uses of thereof.
    Type: Application
    Filed: May 14, 2019
    Publication date: January 23, 2020
    Inventors: Peter Cameron Colosi, Silvia Ramirez