Patents by Inventor Silvia Rasi

Silvia Rasi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Truncated secretory aspartyl proteinase 2
    Patent number: 9610334
    Abstract: The present invention relates to an isolated truncated form of the secretory aspartyl proteinase 2, as well as to nucleic acid molecules encoding same. The present invention also relates to a composition comprising an isolated truncated form of the secretory aspartyl proteinase 2, as well as to nucleic acid molecules encoding same.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: April 4, 2017
    Assignees: Istituto Superiore di Sanita, NovaDigm Therapeutics, Inc.
    Inventors: Rinaldo Zurbriggen, Flavia De Bernardis, Antonio Cassone, Silvia Rasi
  • Truncated Secretory Aspartyl Proteinase 2
    Publication number: 20140193445
    Abstract: The present invention relates to an isolated truncated form of the secretory aspartyl proteinase 2, as well as to nucleic acid molecules encoding same. The present invention also relates to a composition comprising an isolated truncated form of the secretory aspartyl proteinase 2, as well as to nucleic acid molecules encoding same.
    Type: Application
    Filed: March 19, 2014
    Publication date: July 10, 2014
    Applicants: Istituto Superiore Di Sanita, Pevion Biotech Ltd.
    Inventors: Rinaldo Zurbriggen, Flavia De Bernardis, Antonio Cassone, Silvia Rasi
  • Truncated secretory aspartyl proteinase 2
    Patent number: 8715698
    Abstract: The present invention relates to an isolated truncated form of the secretory aspartyl proteinase 2, as well as to nucleic acid molecules encoding same. The present invention also relates to a composition comprising an isolated truncated form of the secretory aspartyl proteinase 2, as well as to nucleic acid molecules encoding same.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: May 6, 2014
    Assignees: Pevion Biotech, AG, Istituto Superiore di Sanita
    Inventors: Rinaldo Zurbriggen, Flavia de Bernardis, Antonio Cassone, Silvia Rasi
  • Lyophilization of Virosomes
    Publication number: 20140072616
    Abstract: The present invention relates to biologically active compositions and methods for the lyophilization and reconstruction of virosomes comprising special membrane compositions. These compositions are essential to the invention and provide superior freeze-drying stress-resistance for the virosomes of the invention.
    Type: Application
    Filed: August 8, 2013
    Publication date: March 13, 2014
    Applicant: Pevion Biotech Ltd.
    Inventors: Rinaldo Zurbriggen, Mario Amacker, Silvia Rasi
  • Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof
    Patent number: 8367077
    Abstract: The present invention relates to virosomes comprising hemagglutinin (HA) with improved fusion activity. Preferably, the HA comprised in said virosomes was derived from influenza virus produced in a cell line. The present invention also relates to compositions and a kit comprising the virosomes according to the invention. Further, the present invention relates to uses and methods involving said virosomes, as well as to a method for preparing same.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: February 5, 2013
    Assignee: Pevion Biotech, AG
    Inventors: Rinaldo Zurbriggen, Christian Moser, Andreas Kammer, Mario Amacker, Nicole Westerfeld, Silvia Rasi
  • Virosomes Comprising Hemagglutinin Derived from an Influenza Virus Produced in a Cell Line, Compositions, Methods of Manufacturing, Use Thereof
    Publication number: 20110045057
    Abstract: The present invention relates to virosomes comprising hemagglutinin (HA) with improved fusion activity. Preferably, the HA comprised in said virosomes was derived from influenza virus produced in a cell line. The present invention also relates to compositions and a kit comprising the virosomes according to the invention. Further, the present invention relates to uses and methods involving said virosomes, as well as to a method for preparing same.
    Type: Application
    Filed: June 13, 2008
    Publication date: February 24, 2011
    Inventors: Rinaldo Zurbriggen, Christian Moser, Silvia Rasi, Andreas Kammer, Mario Amacker, Nicole Westerfeld
  • TRUNCATED SECRETORY ASPARTYL PROTEINASE 2
    Publication number: 20100285109
    Abstract: The present invention relates to a truncated form of the secretory aspartyl proteinase 2 (Sap2), as well as to nucleic acid molecules encoding same. This truncated Sap2 polypeptide (tSap2) is surprisingly stable and devoid of enzymatic activity but retains full immunogenicity upon intravaginal administration and confers full protection against intravaginal challenge by the Candida fungus. The present invention further relates to compositions comprising tSap2 and to the use of tSap2 in the preparation of such compositions.
    Type: Application
    Filed: September 19, 2008
    Publication date: November 11, 2010
    Applicants: Pevion Biotech Ltd., Istituto Superiore di Sanita
    Inventors: Rinaldo Zurbriggen, Flavia De Bernardis, Antonio Cassone, Silvia Rasi
  • Lyophilization of virosomes
    Publication number: 20080268028
    Abstract: The present invention relates to biologically active compositions and methods for the lyophilization and reconstruction of virosomes comprising special membrane compositions. These compositions are essential to the invention and provide superior freeze-drying stress-resistance for the virosomes of the invention.
    Type: Application
    Filed: June 28, 2007
    Publication date: October 30, 2008
    Applicant: Pevion Biotech Ltd.
    Inventors: Rinaldo Zurbriggen, Mario Amacker, Silvia Rasi