Patents by Inventor Simão Pedro DE PINHO SOARES

Simão Pedro DE PINHO SOARES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MICROBIAL PRODUCTION OF TYROSOL AND SALIDROSIDE
    Publication number: 20240132921
    Abstract: The invention relates to a method for production of tyrosol, wherein a transgenic bacterial cell that heterologously expresses phenylpyruvate decarboxylase and that overexpresses phospho-2-dehydro-3-deoxyheptonate and prephenate dehydrogenase, and wherein pheAL and feaB are both inactivated or removed, is grown in a medium comprising a metabolic precursor of phosphoenolpyruvate (PEP) and erythrose 4-phosphate (E4P), particularly glucose, and optionally, phenylalanine as a supplement; and tyrosol is extracted from said medium. The invention also relates to a method for production of salidroside, wherein the transgenic cell additionally heterologously expresses uridine diphosphate dependent glycosyltransferase (UGT85A1, EC:2.4.1.
    Type: Application
    Filed: February 8, 2022
    Publication date: April 25, 2024
    Applicant: SILICOLIFE LDA.
    Inventors: Simão Pedro DE PINHO SOARES, Joana Margarida SILVA GOMES, Cristiana DA SILVA FARIA, Isabel Cristina DE ALMEIDA PEREIRA DA ROCHA, Paulo Ricardo CARVALHO VILAÇA
  • METHOD FOR N-BUTANOL PRODUCTION USING HETEROLOGOUS EXPRESSION OF ANAEROBIC PATHWAYS
    Publication number: 20210017550
    Abstract: The present invention relates to a method for the production of n-butanol using a transgenic cell with heterologous expression of 2-hydroxyglutarate dehydrogenase, glutaconate-CoA transferase, (R)-2-hydroxyglutaryl-CoA dehydrogenase, glutaryl CoA dehydrogenase, trans-2-enoyl-CoA reductase (NAD+) and bifunctional aldehyde/alcohol dehydrogenase (NAD+).
    Type: Application
    Filed: March 28, 2019
    Publication date: January 21, 2021
    Applicants: SILICOLIFE LDA., UNIVERSIDADE DO MINHO
    Inventors: Isabel Cristina DE ALMEIDA PEREIRA DA ROCHA, Miguel Francisco DE ALMEIDA PEREIRA DA ROCHA, Ana Sofia ARAÚJO FERREIRA, Filipe Alexandre Wang LIU, Rui Miguel Pinheiro DA SILVA PEREIRA, Paulo Ricardo CARVALHO VILAÇA, Simão Pedro DE PINHO SOARES