Patents by Inventor Sima S. Bilge

Sima S. Bilge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Escherichia coli O157:H7 epithelial adhesion and vaccine
    Patent number: 6040421
    Abstract: Polypeptides encoded by a continuous segment of chromosomal DNA from E. coli O157:H7, isolated on plasmid pSC(overlap) (ATCC No. 69648), that encodes an adhesin (SEQ ID NO:5) that mediates bacterial colonization of bovine intestines, vaccines derived therefrom, and antibodies directed against the adhesin.
    Type: Grant
    Filed: June 16, 1998
    Date of Patent: March 21, 2000
    Assignees: Children's Hospital and Medical Center, University of Washington, University Research Foundation
    Inventors: Phillip I. Tarr, Sima S. Bilge, Thomas E. Besser, James C. Vary, Jr.
  • Escherichia coli O157:H7 epithelial adhesin
    Patent number: 5798260
    Abstract: A continuous segment of chromosomal DNA from E. coli O157:H7, isolated on plasmid pSC(overlap) (ATCC No. 69648), encodes an adhesin (SEQ ID NO:4) that mediates bacterial colonization of bovine intestines.
    Type: Grant
    Filed: March 26, 1997
    Date of Patent: August 25, 1998
    Assignees: Children's Hospital and Medical Center, University of Washington, Washington State University Research Foundation
    Inventors: Phillip I. Tarr, Sima S. Bilge, Thomas E. Besser, James C. Vary, Jr.
  • Nucleic acid probes for detecting E. coli O157:H7
    Patent number: 5654417
    Abstract: An isolated nucleic acid molecule that hybridizes under stringent conditions to SEQ ID NO:1 or its complement and to the DNA of enterohemorrhagic E. coli O157:H7 but not to the DNA of enteropathogenic E. coli O55:H7.
    Type: Grant
    Filed: April 14, 1995
    Date of Patent: August 5, 1997
    Assignees: Children's Hospital and Medical Center, University of Washington
    Inventors: Phillip I. Tarr, Sima S. Bilge, James C. Vary, Jr.