Abstract: An FAP/CD40 binding molecule and the medicinal use thereof. Specifically, provided are an FAP binding molecule, a CD40 binding molecule and an FAP/CD40 binding molecule, a method for preventing and treating diseases (such as tumors or cancers) using same, and the medicinal use thereof.

Abstract: A method for analyzing microarray images in an automatic and parallel fashion is provided. Optimal gridding is achieved by an automatic and robust identification of fiducial marker spots, even if spots are of poor quality, poorly imaged and/or there is rotation or shifting of the well. Spot region is correctly captured through an active-contour image segmentation without an estimate of spot size. The circularity of spot regions is used as a crucial indicator of spot quality. Spots of poor quality are identified as outliers when the circularity is below a threshold. Parallel computing is utilized to accelerate the image analysis.

Abstract: Provided is a multispecific antigen binding protein. Provided is a multispecific antigen binding protein comprising one or more amino acid substitutions at CH1 and CL, a composition comprising same, a preparation method therefor, and a medical use thereof. The specific antigen binding protein effectively reduces the mismatching of light chains.

Abstract: The present disclosure relates to anti-CD25 antibodies, antigen-binding fragments thereof, and medical uses thereof. Specifically, the present disclosure relates to anti-CD25 antibodies and their use for preparing anti-tumor drugs.

Abstract: Apparatus and methods for super-resolution imaging of extended objects utilize a scanned illumination source with a small spot size. Sub-images composed of highly-overlapping point spread functions are captured and each sub-image is iteratively compared to a series of brightness combinations of template point spread functions in a dictionary. The dictionary is composed of highly-overlapping point spread functions. Each sub-image is associated with a best-match template combination solution, and the best-match reconstructions created by best-match solutions are combined into a super-resolution image of the object.

Abstract: Apparatus and methods for super-resolution imaging of extended objects utilize a scanned illumination source with a small spot size. Sub-images composed of highly-overlapping point spread functions are captured and each sub-image is iteratively compared to a series of brightness combinations of template point spread functions in a dictionary. The dictionary is composed of highly-overlapping point spread functions. Each sub-image is associated with a best-match template combination solution, and the best-match reconstructions created by best-match solutions are combined into a super-resolution image of the object.