Patents by Inventor Simeon Santourlidis

Simeon Santourlidis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Determination of the normalized degree of DNA methylation
    Patent number: 9850528
    Abstract: The present invention provides oligonucleotides and processes for determining the normalized methylation level of DNA, and for determining the relative methylation level of DNA between at least two samples. The invention makes use of the random distribution of transposons in the genome. The disclosed oligonucleotides and processes are of importance, in particular, for clinical diagnostics.
    Type: Grant
    Filed: January 21, 2010
    Date of Patent: December 26, 2017
    Assignee: HEINRICH-HEINE-UNIVERSITÄT DÜSSELDORF
    Inventor: Simeon Santourlidis
  • QUALITY DETERMINATION OF STEM CELLS
    Publication number: 20140004512
    Abstract: The invention relates to a method for determining the quality of a pluripotent stem cell, comprising the following steps: measuring the DNA methylation of at least one CpG in a CpG island in at least two genes of the pluripotent stem cell, comparing it to the DNA methylation of the at least one CpG in a CpG island in the at least two genes of at least one reference cell, wherein the genes are located on different chromosomes and belong to the gene family of olfactory receptor genes.
    Type: Application
    Filed: October 11, 2011
    Publication date: January 2, 2014
    Inventor: Simeon Santourlidis
  • DETERMINATION OF THE DEGREE OF DNA METHYLATION
    Publication number: 20110318739
    Abstract: The present invention provides oligonucleotides and processes for determining the normalized methylation level of DNA, and for determining the relative methylation level of DNA between at least two samples. The invention makes use of the random distribution of transposons in the genome. The disclosed oligonucleotides and processes are of importance, in particular, for clinical diagnostics.
    Type: Application
    Filed: January 21, 2010
    Publication date: December 29, 2011
    Applicant: HEINRICH-HEINE-UNIVERSITÄT DÜSSELDORF
    Inventor: Simeon Santourlidis