Patents by Inventor Simha Shemesh

Simha Shemesh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High throughput assay for monitoring polycation or polyanion molecular weight, degradation or synthesis
    Patent number: 6630295
    Abstract: A method of testing an agent for its potential at modulating induction of a molecular weight change of a first polyion is disclosed. The method is effected by (a) subjecting the first polyion to conditions under-which the first polyion undergoing the molecular weight change in a presence, in an absence or under several different concentrations of the agent; (b) interacting the first polyion with a second polyion having an opposite charge, the second polyion being fluorescently labeled; (c) providing reaction conditions so as to allow molecular weight discriminative interaction between the first polyion and the second polyion; and (d) employing a fluorescence polarization assay for determining a modulating effect of the agent on the induction of the molecular weight change of the first polyion.
    Type: Grant
    Filed: January 4, 2001
    Date of Patent: October 7, 2003
    Assignee: Insight Strategy & Marketing Ltd.
    Inventors: Raphael Mayer, Simha Shemesh, Maty Ayal-Hershkovitz
  • High throughput assay for monitoring polycation or polyanion molecular weight, degradation or synthesis
    Publication number: 20020115071
    Abstract: A method of testing an agent for its potential at modulating induction of a molecular weight change of a first polyion is disclosed. The method is effected by (a) subjecting the first polyion to conditions under-which the first polyion undergoing the molecular weight change in a presence, in an absence or under several different concentrations of the agent; (b) interacting the first polyion with a second polyion having an opposite charge, the second polyion being fluorescently labeled; (c) providing reaction conditions so as to allow molecular weight discriminative interaction between the first polyion and the second polyion; and (d) employing a fluorescence polarization assay for determining a modulating effect of the agent on the induction of the molecular weight change of the first polyion.
    Type: Application
    Filed: January 4, 2001
    Publication date: August 22, 2002
    Applicant: Insight Strategy & Marketing Ltd.
    Inventors: Raphael Mayer, Simha Shemesh, Maty Ayal-Hershkovitz