Patents by Inventor Simon A. Houston

Simon A. Houston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunogenic TP0751 fragments
    Patent number: 9913889
    Abstract: The present application provides methods of stimulating an immune response, such as a protective immune response against Treponema pallidum infection. Such methods utilize fragments of the Tp0751 protein (such as any of SEQ ID NOs: 3-10, those N-terminally truncated from amino acids 1 through 77, 1 through 114, or anywhere in between, e.g., those that start at any amino acid from 78 to 115). In some examples, a Tp0751 protein fragment has a mutated HEXXH site (HEXXH is the wild-type sequence). Also provided are the isolated soluble Tp0751 protein fragments that include a wild-type or mutated HEXXH site, as well as nucleic acids encoding such proteins and kits that include such proteins.
    Type: Grant
    Filed: January 12, 2016
    Date of Patent: March 13, 2018
    Assignee: UVic Industry Partnerships Inc.
    Inventors: Caroline E. Cameron, Rebecca M. Hof, Simon A. Houston, Martin John Boulanger
  • IMMUNGENIC TP0751 FRAGMENTS
    Publication number: 20160129100
    Abstract: The present application provides methods of stimulating an immune response, such as a protective immune response against Treponema pallidum infection. Such methods utilize fragments of the Tp0751 protein (such as any of SEQ ID NOs: 3-10, those N-terminally truncated from amino acids 1 through 77, 1 through 114, or anywhere in between, e.g., those that start at any amino acid from 78 to 115). In some examples, a Tp0751 protein fragment has a mutated HEXXH site (HEXXH is the wild-type sequence). Also provided are the isolated soluble Tp0751 protein fragments that include a wild-type or mutated HEXXH site, as well as nucleic acids encoding such proteins and kits that include such proteins.
    Type: Application
    Filed: January 12, 2016
    Publication date: May 12, 2016
    Applicant: UVic Industry Partnerships Inc.
    Inventors: Caroline E. Cameron, Rebecca M. Hof, Simon A. Houston, Martin John Boulanger
  • Novel purified polypeptides from bacteria
    Publication number: 20050214773
    Abstract: The present invention relates to polypeptide targets for pathogenic bacteria. The invention also provides biochemical and biophysical characteristics of those polypeptides.
    Type: Application
    Filed: March 22, 2004
    Publication date: September 29, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Muhammad Alam, Megan Domagala, Simon Houston, Robert Lam, Qin Li, Kathleen Nethery-Brokx, Ivy Ng, Benjamin Pinder, Cristina Viola, Olga Wrezel, Dhushy Kanagarajah, Kamran Mansoury, Sasha Necakov, Francois Vallee, Merry-Lynn McDonald
  • Novel purified polypeptides from Streptococcus pneumoniae
    Publication number: 20050187718
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: August 20, 2004
    Publication date: August 25, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Teresa Clarke, Matthew Kimber, Vivek Sharma, Simon Houston, Kamran Mansoury
  • Novel purified polypeptides from bacteria
    Publication number: 20050181388
    Abstract: The present invention relates to polypeptide targets for pathogenic bacteria. The invention also provides biochemical and biophysical characteristics of those polypeptides.
    Type: Application
    Filed: October 4, 2004
    Publication date: August 18, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Muhammad Alam, Cheryl Arrowsmith, Donald Awrey, Bryan Beattie, Kristina Buzadzija, Veronica Canadien, Megan Domagala, Simon Houston, Dhushy Kanagarajah, Qin Li, Kamran Mansoury, Merry-Lynn McDonald, Kathleen Nethery-Brokx, Ivy Ng, Hui Ouyang, Benjamin Pinder, Dawn Richards, Matthew Tai, Rosanne Thalakada, Francois Vallee, Cristina Virag
  • Novel purified polypeptides from bacteria
    Publication number: 20050181464
    Abstract: The present invention relates to polypeptide targets for pathogenic bacteria. The invention also provides biochemical and biophysical characteristics of those polypeptides.
    Type: Application
    Filed: September 29, 2004
    Publication date: August 18, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Muhammad Alam, Cheryl Arrowsmith, Donald Awrey, Bryan Beattie, Kristina Buzadzija, Teresa Clarke, Megan Domagala, Simon Houston, Dhushy Kanagarajah, Qin Li, Kamran Mansoury, Merry-Lynn McDonald, Kathleen Nethery-Brokx, Ivy Ng, Hui Ouyang, Dawn Richards, Francois Vallee, Cristina Virag
  • Novel purified polypeptides from staphylococcus aureus
    Publication number: 20050164363
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: July 30, 2004
    Publication date: July 28, 2005
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Simon Houston, Matthew Kimber
  • Novel purified polypeptides from pseudomonas aeruginosa
    Publication number: 20050164362
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: June 21, 2004
    Publication date: July 28, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Muhammad Alam, Megan Domagala, Simon Houston, Matthew Kimber, Benjamin Pinder, Francois Vallee, Olga Wrezel, Donald Awrey, Bryan Beattie
  • Novel purified polypeptides from Streptococcus pneumoniae
    Publication number: 20050158732
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified proteins comprising amino acid sequences set forth within. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: June 18, 2004
    Publication date: July 21, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Muhammad Alam, Simon Houston, Matthew Kimber, Robert Lam, Ivy Ng, Benjamin Pinder