Patents by Inventor Simon Adrian Wells

Simon Adrian Wells has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8828208
    Abstract: An apparatus for sensing of an interaction of a molecular entity with a membrane protein in a lipid bilayer comprises an array of sensor elements (21) arranged to output an electrical signal that is dependant on occurrences of the interaction. A detection circuit (3) comprised detection channels (30) capable of amplifying an electrical signal from a sensor element. More sensor elements (21) are provided than detection channels (30), and detection channels (30) are selectively connected to sensor elements (21) that have acceptable quality of performance in that a lipid bilayer is formed and that an acceptable number of membrane proteins are inserted, on the basis of the amplified electrical signals that are output from the detection channels. This improves the efficiency of utilization of the detection channels, due to inefficiency in the utilization of the sensor elements, resulting in a reduction in the cost of the apparatus and the ability to perform sensing using relatively small samples.
    Type: Grant
    Filed: April 19, 2010
    Date of Patent: September 9, 2014
    Assignee: Oxford Nanopore Technologies Limited
    Inventors: Antonio Canas, Simon Adrian Wells
  • Publication number: 20120133354
    Abstract: An apparatus for sensing of an interaction of a molecular entity with a membrane protein in a lipid bilayer comprises an array of sensor elements (21) arranged to output an electrical signal that is dependant on occurrences of the interaction. A detection circuit (3) comprised detection channels (30) capable of amplifying an electrical signal from a sensor element. More sensor elements (21) are provided than detection channels (30), and detection channels (30) are selectively connected to sensor elements (21) that have acceptable quality of performance in that a lipid bilayer is formed and that an acceptable number of membrane proteins are inserted, on the basis of the amplified electrical signals that are output from the detection channels. This improves the efficiency of utilisation of the detection channels, due to inefficiency in the utilisation of the sensor elements, resulting in a reduction in the cost of the apparatus and the ability to perform sensing using relatively small samples.
    Type: Application
    Filed: April 19, 2010
    Publication date: May 31, 2012
    Applicant: OXFORD NANOPORE TECHNOLOGIES LIMITED
    Inventors: Antonio Canas, Simon Adrian Wells
  • Patent number: 6483113
    Abstract: A spectrometer, typically an FT-IR spectrometer, is operated in a continuous mode so that it is carrying out scans on a continuous basis. The acquired data is stored and can be retrieved when a sample measurement is made. This improves the response of the instrument.
    Type: Grant
    Filed: August 26, 1999
    Date of Patent: November 19, 2002
    Assignee: Wellesley Inernational C.V.
    Inventors: George Robert Sealy, Simon Adrian Wells