Abstract: Disclosed is a process for the preparation of certain intermediates, e.g. a process for preparing a compound of formula (I) wherein, R1, R2 and X1 are as defined in the description, and which intermediate and processes are useful in the preparation of a BTK inhibitor, such as ibrutinib.

Abstract: The present application generally relates to several processes for the preparation of (6R,10S)-10-{4-[5-chloro-2-(4-chloro-1H-1,2,3-triazol-1-yl)phenyl]-6-oxo-1(6H)-pyrimidinyl}-1-(difluoromethyl)-6-methyl-1,4,7,8,9,10-hexahydro-11,15-(metheno)pyrazolo[4,3-b][1,7]diazacyclotetradecin-5(6H)-one: Compound (I).

Abstract: Disclosed is a process for the preparation of certain intermediates, e.g. the following compound: which intermediate and processes are useful in the preparation of a BTK inhibitor, such as ibrutinib.

Abstract: Disclosed is a process for the preparation of certain intermediates, e.g. a process R for preparing a compound of formula (I) wherein, R1, R2 and X1 are as defined in the description, and which intermediate and processes are useful in the preparation of a BTK inhibitor, such as ibrutinib.

Abstract: Highly efficient methods are provided for preparing key intermediates in the synthesis of Compound (I), which are broadly applicable and can provide selected components having a variety of substituents groups.

Abstract: A motor-transmission arrangement for an adjusting device for adjusting two components adjustable relative to each other can include a planetary gear system having a planetary carrier, a planetary gear with planetary gear toothing and which is rotatably mounted in the planetary carrier and with a ring gear with an internal toothing which engages with the planetary gear toothing. An electric motor can have a motor shaft which can be rotated about a motor shaft axis, which shaft interacts with the planetary gear system, and a housing which is closed with first and second housing covers in which the motor shaft is mounted via a first bearing section and a second bearing section.

Abstract: A tank valve for installation on a compressed gas container has a base body having a shared gas connection for refueling/extraction which is divided inside the base body into a refueling line and an extraction line as part of an extraction path, and has an extraction valve in the extraction line. The tank valve has a check valve disposed in the extraction path in series with the extraction valve, blocking the flow against the flow direction when gas is extracted.

Abstract: A bearing assembly for supporting a helical-wheel shaft of a helical planetary gear, in particular an adjustment device in vehicles for adjusting two mutually adjustable vehicle parts, wherein the helical-wheel planetary gear is a helical-wheel shaft with a helical-gear toothing, which shaft is rotatably mounted about a helical-wheel shaft axis, and a planetary carrier comprising at least three helical planetary gears, each rotatably mounted in the planetary carrier about a planetary gear axis, and each having a planetary gear toothing, wherein the helical gear planetary axes extend obliquely to the helical-wheel shaft axis, and the bearing assembly for supporting the helical gear shaft has a first bearing section and a second bearing section, wherein the first bearing section consists of an axial and radial bearing, and the second bearing section consists of helical-wheel planetary gears, wherein the planetary gear toothing in the second bearing section meshes with the helical-gear toothing.

Abstract: A helical planetary gear for a helical planetary gear unit for an adjusting device in vehicles for adjusting two components which are adjustable with respect to one another, wherein the helical planetary gear defines a planetary gear axis and comprises planetary gear toothing having a first planetary gear toothing end and a second planetary gear toothing end, wherein the first planetary gear toothing end and the second planetary gear toothing end are arranged apart from one another in relation to the planetary gear axis, and the planetary gear toothing has a diameter that increases or decreases proceeding from the first planetary gear toothing end to the second planetary gear toothing end and further relates to an internal helical gear for a helical planetary gear unit as well as a helical planetary gear unit for an adjusting unit for adjusting two components which are adjustable with respect to one another.

Abstract: An electrical connection device for an electromagnetic valve that has a temperature sensor for sensing the temperature of a medium. The electrical connection device includes an electrical contact plug. The electrical contact plug is part of a common housing which additionally includes an actuator coil for the electromagnetic valve as well as a plug contact for making electrical contact with the temperature sensor when the housing is mounted onto the electromagnetic valve.

Abstract: A planet carrier for supporting at least one planet wheel in a planetary gear for an adjustment unit for adjusting two components adjustable in relation to one another. The planet wheel comprises a planet wheel axle, which has first and second axle portions protruding beyond the planet wheel, and the planet carrier comprises a tubular main body with a passage that penetrates the main body, first and second support portions originating from the passage, where the first and second support portions are designed for the rotational accommodation of the first and the second axle portions. The planet carrier can include protrusions that fix the first and the second axle portions in the support portions.

Abstract: A pinion cage for supporting at least one spiral gear planet wheel in a spiral gear planetary gear train for an adjustment device for adjusting two structural components which can be adjusted relative to one another, wherein the spiral gear planet wheel comprises a planet wheel axle which comprises a first axial section extending over the spiral gear planet wheel and comprises a second axial section extending over the spiral gear planet wheel, and the pinion cage comprises a tubular base body which defines a pinion cage axis, at least one perforation arranged in the base body and penetrating through it, a first support section starting from the perforation, a second support section starting from the perforation, wherein the first and the second support sections are constructed for rotatably receiving the first and the second axial sections and are arranged in such a manner that the planet wheel axle runs in a twisted manner to the pinion cage axis if the axial sections are received in the support sections, an

Abstract: A motor-transmission arrangement in particular for an adjustment device in vehicles for adjusting two vehicle parts which can be adjusted relative to one another can include a planetary transmission with at least one pinion cage, at least one planet wheel which is rotatably supported in the pinion cage and with a planet wheel cogging, and with at least one hollow gear with an inside cogging which is engaged with the planet wheel cogging, and an electromotor with a motor shaft which can rotate about a motor shaft axle and which comprises a motor shaft cogging arranged directly on the motor shaft, which cogging is engaged with the planet wheel cogging. The disclosure also relates to an adjustment device with such a motor-transmission arrangement and to the usage of such a motor-transmission arrangement in adjustment devices.

Abstract: A motor-transmission arrangement for an adjusting device for adjusting two components adjustable relative to each other can include a planetary gear system having a planetary carrier, a planetary gear with planetary gear toothing and which is rotatably mounted in the planetary carrier and with a ring gear with an internal toothing which engages with the planetary gear toothing. An electric motor can have a motor shaft which can be rotated about a motor shaft axis, which shaft interacts with the planetary gear system, and a housing which is closed with first and second housing covers in which the motor shaft is mounted viaa first bearing section and a second bearing section.

Abstract: A bearing assembly for supporting a helical-wheel shaft of a helical planetary gear, in particular an adjustment device in vehicles for adjusting two mutually adjustable vehicle parts, wherein the helical-wheel planetary gear is a helical-wheel shaft with a helical-gear toothing, which shaft is rotatably mounted about a helical-wheel shaft axis, and a planetary carrier comprising at least three helical planetary gears, each rotatably mounted in the planetary carrier about a planetary gear axis, and each having a planetary gear toothing, wherein the helical gear planetary axes extend obliquely to the helical-wheel shaft axis, and the bearing assembly for supporting the helical gear shaft has a first bearing section and a second bearing section, wherein the first bearing section consists of an axial and radial bearing, and the second bearing section consists of helical-wheel planetary gears, wherein the planetary gear toothing in the second bearing section meshes with the helical-gear toothing.

Abstract: The invention relates to a tank valve (4) for mounting on a pressurized-gas container (3), having a main body (5), having multiple functional subassemblies for the refilling of the pressurized-gas accumulator (3), for the removal of gas from the pressurized-gas accumulator (3) and the implementation of safety and operating functions, wherein one of the functional subassemblies is formed as an extraction valve (6), and wherein at least one of the other functional subassemblies is formed as a check valve (14, 17). The tank valve according to the invention is characterized in that both the extraction valve (6) and the at least one check valve (14, 17) have in each case one valve seat carrier (22) with a valve seat (21) and one valve body (19), wherein that part of the valve seat carrier (22) which interacts with the valve body (19) has a sealing lip (23), which projects in an axial direction, as part of the valve seat (21).

Abstract: The invention relates to a tank valve (4) for installation on a compressed gas container (3), having a base body (5), having a shared gas connection (16) for refueling/extraction, which is divided inside the base body (5) into a refueling line (24) and an extraction line (25) as part of an extraction path, and having an extraction valve (9) in the extraction line (25). The tank valve according to the invention is characterized in that a check valve (26) is arranged in the extraction path in series with the extraction valve (9), blocking the flow against the flow direction (A) when gas is extracted.

Abstract: A helical planetary gear for a helical planetary gear unit for an adjusting device in vehicles for adjusting two components which are adjustable with respect to one another, wherein the helical planetary gear defines a planetary gear axis and comprises planetary gear toothing having a first planetary gear toothing end and a second planetary gear toothing end, wherein the first planetary gear toothing end and the second planetary gear toothing end are arranged apart from one another in relation to the planetary gear axis, and the planetary gear toothing has a diameter that increases or decreases proceeding from the first planetary gear toothing end to the second planetary gear toothing end and further relates to an internal helical gear for a helical planetary gear unit as well as a helical planetary gear unit for an adjusting unit for adjusting two components which are adjustable with respect to one another.

Abstract: A planet carrier for supporting at least one planet wheel in a planetary gear for an adjustment unit for adjusting two components adjustable in relation to one another. The planet wheel comprises a planet wheel axle, which has first and second axle portions protruding beyond the planet wheel, and the planet carrier comprises a tubular main body with a passage that penetrates the main body, first and second support portions originating from the passage, where the first and second support portions are designed for the rotational accommodation of the first and the second axle portions. The planet carrier can include protrusions that fix the first and the second axle portions in the support portions.

Abstract: A pinion cage for supporting at least one spiral gear planet wheel in a spiral gear planetary gear train for an adjustment device for adjusting two structural components which can be adjusted relative to one another, wherein the spiral gear planet wheel comprises a planet wheel axle which comprises a first axial section extending over the spiral gear planet wheel and comprises a second axial section extending over the spiral gear planet wheel, and the pinion cage comprises a tubular base body which defines a pinion cage axis, at least one perforation arranged in the base body and penetrating through it, a first support section starting from the perforation, a second support section starting from the perforation, wherein the first and the second support sections are constructed for rotatably receiving the first and the second axial sections and are arranged in such a manner that the planet wheel axle runs in a twisted manner to the pinion cage axis if the axial sections are received in the support sections, an