Patents by Inventor Simon Ametamey

Simon Ametamey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isomerically pure F-labelled tetrahydrofolates
    Patent number: 12023390
    Abstract: The present invention is directed towards isomerically pure 18F-labelled (6S)- or (6R)-5-methyltetrahydrofolate radiopharmaceuticals, wherein the phenyl group within the folate structure, has been replaced by an 18F-labelled N-heterocycle, for use in diagnostic imaging of a cell or population of cells expressing a folate-receptor in vitro or in vivo or for use in monitoring of cancer or inflammatory and autoimmune diseases and therapy thereof.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: July 2, 2024
    Assignee: Merck Patent GmbH
    Inventors: Rudolf Moser, Viola Groehn, Cristina Mueller, Roger Schibli, Simon Ametamey, Silvan Boss
  • Compounds and methods for F labeled agents
    Patent number: 8557776
    Abstract: The present invention relates to novel compounds suitable for or already radiolabeled with 18F, methods of making such compounds and use of such compounds for diagnostic imaging. Such labeled compounds are characterized by Formula II, wherein the substituents G, Q, L, Y and U have the meaning as defined in the specification and claims.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: October 15, 2013
    Assignee: Bayer Pharma AG
    Inventors: Lutz Lehmann, Ananth Srinivasan, Thomas Brumby, Detlef Suelzle, Timo Stellfeld, Keith Graham, Mylene Tania Karramkam, Simon Ametamey
  • RADIOFLUORINATION
    Publication number: 20090035215
    Abstract: The present invention relates to novel compounds suitable for or already radiolabeled with 18F, methods of making such compounds and use of such compounds for diagnostic imaging. Such labeled compounds are characerized by Formula II, wherein the moieties F, R1, R2, B1,2, Y1,2, Z1,2 and E have the meaning as defined in the specification and claims.
    Type: Application
    Filed: September 7, 2007
    Publication date: February 5, 2009
    Inventors: Ananth Srinivasan, Ulrich Klar, Lutz Lehmann, Ulrike Voigtmann, Timo Stellfeld, Aileen Hohne, Linjing Mu, Simon Ametamey
  • COMPOUNDS AND METHODS FOR 18F LABELED AGENTS
    Publication number: 20080292548
    Abstract: The present invention relates to novel compounds suitable for or already radiolabeled with 18F, methods of making such compounds and use of such compounds for diagnostic imaging. Such labeled compounds are characterized by Formula II, wherein the substituents G, Q, L, Y and U have the meaning as defined in the specification and claims.
    Type: Application
    Filed: September 7, 2007
    Publication date: November 27, 2008
    Inventors: Lutz Lehmann, Ananth Srinivasan, Thomas Brumby, Detlef Suelzle, Timo Stellfeld, Keith Graham, Mylene Karramkam, Simon Ametamey