Abstract: A hemofilter system. In one embodiment, the hemofilter system includes a container having a first surface, a second surface, and one or more wall surfaces, the first surface, the second surface and the one or more wall surfaces defining a volume; an input port in fluid communication with the first surface; an output port in fluid communication with the second surface; a filter bed comprising a plurality of planar magnetic meshes stacked in close juxtaposition and positioned within the container volume and coplanar with the first and second surfaces; a first magnet positioned on a first surface of the container; a second magnet positioned on the second surface of the container; a first input conduit in fluid communication with the input port; and a first output conduit in fluid communication with the output port. In another embodiment, the hemofilter system includes a pump in the input conduit.

Abstract: Compounds of Formula (I): wherein R1, R3, R11, R12, X, Y1, Y2, Y3, Y4 and are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring anti-apoptotic inhibitors.

Abstract: Disclosed herein are agricultural compositions comprising plant messenger packs (PMPs), methods for using the same, and methods and related bioreactors for manufacturing PMPs.

Abstract: A solidified melt extrudate comprising an active pharmaceutical ingredient in an amorphous form and a combination of at least two polymers.

Abstract: A distributed imaging system for augmented reality devices is disclosed. The system includes a computing module in communication with a plurality of spatially distributed sensing devices. The computing module is configured to process input images from the sensing devices based on performing a local feature matching computation to generate corresponding first output images. The computing module is further configured to process the input images based on performing an optical flow correspondence computation to generate corresponding second output images. The computing module is further configured to computationally combine first and second output images to generate third output images.

Abstract: A treatment apparatus for a cataract treatment of an eye includes a modular intraocular lens including a first part, which includes a haptic configured to contact a capsular bag of the eye in a region of the equator of the capsular bag and thereby to span the capsular bag, and a second part, which includes an optic body, and has a convergence state, in which the second part contacts the first part, and a spaced-apart state, in which the second part is arranged spaced apart from the first part, a measurement system configured to determine, based on a first measurement, a position of the first part in the eye and in the spaced-apart state of the modular intraocular lens, and a controller configured to determine, based on the position of the first part, a refractive power of the optic body which is to be inserted into the eye.

Abstract: Provided are pharmaceutical compositions and methods for preparing pharmaceutical compositions comprising Ibuprofen using solventless mixing methods. Excess coating material that is not bound to coated Ibuprofen may be removed by a sieving process. Coating and dosing ratios can also be optimized to minimize the amount of excess unbound coating material. Additionally, the compositions can be formulated to preserve the functional coating of coated Ibuprofen and to minimize aeration of Ibuprofen when mixed into suspension.

Abstract: A method for identifying a cutscene in gameplay footage, the method comprising: receiving a first video signal and a second video signal each comprising a plurality of images; creating a first video fingerprint comprising a plurality of signatures, each signature of the plurality of signatures based on at least one image of the plurality of images in the first video signal; creating a second video fingerprint comprising a plurality of signatures, each signature of the plurality of signatures based on at least one image of the plurality of images in the second video signal; comparing the first video fingerprint with the second video fingerprint; and identifying a cutscene when at least a portion of the first video fingerprint has at least a threshold level of similarity with at least a portion of the second video fingerprint.

Abstract: Provided are pharmaceutical compositions and methods for preparing pharmaceutical compositions using solventless mixing methods. Excess coating material that is not bound to a coated API particle may be removed by a sieving process. Coating and dosing ratios can also be optimized to minimize the amount of excess unbound coating material. Specifically, a coating ratio and/or a dosing ratio can be used to minimize the residual amount of excess unbound coating material to minimize agglomeration of coating material during storage. In some embodiments, a pharmaceutical composition is provided, the pharmaceutical composition comprising: 65-85% w/w API particles; 15-30% w/w coating material coating the API particles; and 3-15% w/w matrix surrounding the coated API particles, wherein the pharmaceutical composition comprises a disintegration time rate of less than 10 seconds for at least six months under storage conditions of at least 25° C. and at least 60% relative humidity.

Abstract: This specification discloses the use of an ATR inhibitor, preferably in combination with a taxane, for the treatment of cancer in a particular subset of patients who have previously received immunotherapy.

Abstract: Provided are pharmaceutical compositions and methods for preparing pharmaceutical compositions using solventless mixing methods. Excess coating material that is not bound to a coated API particle may be removed by a sieving process. Coating and dosing ratios can also be optimized to minimize the amount of excess unbound coating material. Specifically, a coating ratio and/or a dosing ratio can be used to minimize the residual amount of excess unbound coating material to minimize agglomeration of coating material during storage. In some embodiments, a pharmaceutical composition is provided, the pharmaceutical composition comprising: 65-85% w/w API particles; 15-30% w/w coating material coating the API particles; and 3-15% w/w matrix surrounding the coated API particles, wherein the pharmaceutical composition comprises a disintegration time rate of less than 10 seconds for at least six months under storage conditions of at least 25° C. and at least 60% relative humidity.

Abstract: Computer-implemented systems and methods for providing contextual game guidance are described herein. An example method includes determining based on contextual information regarding an application an objective of the user; automatically deriving based on the contextual information and the objective contextual guidance to assist the user; generating a user interface having the contextual guidance; and transmitting the user interface to a client device.

Abstract: A wheel assembly bushing for in-wheel electric motors where the bushing includes a hydraulic chamber positioned within a resilient sleeve of the bushing and a helical fluid channel that extends helically about an inner bushing member between first and second fluid channel ends, which are arranged in fluid communication with the hydraulic chamber. An outer body extends annularly about the resilient sleeve, which permits relative movement between the inner bushing member and the outer body. The fluid channel is configured to produce inertance. This inertance, when combined with other damping and stiffness effects of the wheel assembly bushing, provides phase and magnitude shifts between force and velocity, which ultimately reduce magnetic gap deformation in the in-wheel electric motor.

Abstract: A method of constructing and handling a request for a desired data file relating to a broadcast segment of a broadcast signal is described. The method comprises receiving an information signal at a receiving device. The information signal comprises at least a data element, and the data element relates to a segment of the broadcast signal. The method also comprises presenting the data element to a user interface of the receiving device, obtaining a user selection of the data element from the user interface, and constructing and transmitting a request for the desired data file relating to the selected data element, the request including an identifier relating to the desired data file.

Abstract: An apparatus, method, and/or system is provided for conducting an engine shutdown in a circumstance of a runaway engine event. In a condition where an uncontrolled fuel source is present in the ambient air, there may be a risk of a runaway engine condition in an internal combustion engine. Air taken into an intake system of the engine may include an undesired or uncontrolled combustible component. The method, apparatus, and/or system includes steps, control systems, devices, and mechanisms to prevent opening of at least one intake valve or exhaust valve of at least one cylinder of the engine to stop combustion in the chamber, in response to a condition indicating a possible runaway engine event. The indicator may include an engine overspeed condition, or presence of the combustible component in the intake air.

Abstract: Computer-implemented systems and methods for providing contextual game guidance are described herein. An example method includes determining based on contextual information regarding an application an objective of the user; automatically deriving based on the contextual information and the objective contextual guidance to assist the user; generating a user interface having the contextual guidance; and transmitting the user interface to a client device.

Abstract: A method of generating audio-visual content from video game footage is provided. The method comprises obtaining a user-selected audio track and obtaining video game footage. Statistical analysis is performed on the audio track so as to determine an excitement level associated with respective portions of the audio track. Statistical analysis is performed on the video game footage so as to determine an excitement level associated with respective portions of the video game footage. Portions of the video game footage are matched with portions of the audio track, based on a correspondence in determined excitement level. Based on said matching, a combined audio-visual content comprising the portions of the video game footage matched to corresponding portions of the audio track is generated. In this way, calm and exciting moments within the video footage are matched to corresponding moments in the audio track. A corresponding system is also provided.

Abstract: Computer-implemented systems and methods for providing contextual game guidance are described herein. An example method includes determining based on contextual information regarding an application an objective of the user; automatically deriving based on the contextual information and the objective contextual guidance to assist the user; generating a user interface having the contextual guidance; and transmitting the user interface to a client device.