Patents by Inventor Simon Bailey

Simon Bailey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240246935
    Abstract: Disclosed are compounds and salts thereof that bind to and modulate cereblon activity. In some embodiments, the binding and modulation of cereblon results in the degradation of IKAROS family zinc finger proteins (e.g., IKZF2).
    Type: Application
    Filed: October 27, 2023
    Publication date: July 25, 2024
    Inventors: Pengyu Yang, Simon Bailey
  • Patent number: 11878968
    Abstract: Disclosed are compounds and salts thereof that bind to and modulate cereblon activity. In some embodiments, the binding and modulation of cereblon results in the degradation of IKAROS family zinc finger proteins (e.g., IKZF2).
    Type: Grant
    Filed: November 3, 2022
    Date of Patent: January 23, 2024
    Assignee: Plexium, Inc.
    Inventors: Pengyu Yang, Simon Bailey
  • Patent number: 11845770
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. For example, the present invention provides methods of treating immune and/or inflammatory disorders by administering a composition comprising a compound having the structure of Formula (I).
    Type: Grant
    Filed: October 21, 2022
    Date of Patent: December 19, 2023
    Assignees: California Institute of Technology, Holoclara, Inc.
    Inventors: Brian M. Stoltz, Corey M. Reeves, Eduardo J. Martinez, Simon Bailey
  • Publication number: 20230265071
    Abstract: Disclosed are compounds and salts thereof that bind to and modulate cereblon activity. In some embodiments, the binding and modulation of cereblon results in the degradation of IKAROS family zinc finger proteins (e.g., IKZF2).
    Type: Application
    Filed: November 3, 2022
    Publication date: August 24, 2023
    Inventors: Pengyu Yang, Simon Bailey
  • Publication number: 20230135574
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. For example, the present invention provides methods of treating immune and/or inflammatory disorders by administering a composition comprising a compound having the structure of Formula (I).
    Type: Application
    Filed: October 21, 2022
    Publication date: May 4, 2023
    Inventors: Brian M. Stoltz, Corey M. Reeves, Eduardo J. Martinez, Simon Bailey
  • Publication number: 20220409650
    Abstract: Described herein are composition of ascarosides, methods of using them, and the like for inhibiting bacterial population growth or for altering the relative ratio of sub-populations of first and second bacteria in a mixed population of bacteria. The invention is particularly useful, for example, for modifying a microbiome of a patient (e.g., for treatment of gut microbiome dysfunction).
    Type: Application
    Filed: June 3, 2020
    Publication date: December 29, 2022
    Inventors: Andrea Choe, Brian Stoltz, Simon Bailey, Eduardo Martinez
  • Publication number: 20220235086
    Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. For example, the present invention provides methods of treating immune and/or inflammatory disorders by administering a composition comprising a compound having the structure of Formula (I).
    Type: Application
    Filed: May 15, 2020
    Publication date: July 28, 2022
    Inventors: Brian M. Stoltz, Corey M. Reeves, Eduardo J. Martinez, Simon Bailey
  • Patent number: 10520177
    Abstract: A mounting adaptor for an electric light fixture to be mounted on a surface. The mounting adaptor comprising: a base and a joining member each having an interfacing face and an electrical interface, one of the base and the joining member comprising on its interfacing face a groove, the other one of the base and the joining member comprising on its interfacing face a lip adapted to cooperate with the groove thereby providing a capability to assemble releasably the joining member with the base; a locking mechanism adapted to lock the base and the joining member in a mounted position relatively to each other; the base comprising a mounting element adapted to mount the base to the surface; and the joining member comprising a joint element adapted to mount the electric light fixture to the joining member.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: December 31, 2019
    Assignee: LES PRODUITS SUNFORCE INC.
    Inventors: Simon Bailey, Michael Dahan, Leslie Wexelman
  • Patent number: 10168032
    Abstract: A mounting adaptor for an electric light fixture to be mounted on a surface. The mounting adaptor comprising: a base and a joining member each having an interfacing face, one of the base and the joining member comprising on its interfacing face a groove, the other one of the base and the joining member comprising on its interfacing face a lip adapted to cooperate with the groove thereby providing a capability to assemble releasably the joining member with the base; a locking mechanism adapted to lock the base and the joining member in a mounted position relatively to each other; the base comprising a mounting element adapted to mount the base to the surface; and the joining member comprising a joint element adapted to mount the electric light fixture to the joining member.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: January 1, 2019
    Inventors: Simon Bailey, Michael Dahan, Leslie Wexelman
  • Patent number: 9133215
    Abstract: The invention relates to compounds of formula (?) as further defined herein and to the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to the uses thereof. The compounds and salts of the present invention inhibit anaplastic lymphoma kinase (ALK) and/or EML4-ALK and are useful for treating or ameliorating abnormal cell proliferative disorders, such as cancer.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: September 15, 2015
    Assignee: Pfizer Inc.
    Inventors: Simon Bailey, Benjamin Joseph Burke, Michael Raymond Collins, Jingrong Jean Cui, Judith Gail Deal, Robert Louis Hoffman, Qinhua Huang, Ted William Johnson, Robert Steven Kania, John Charles Kath, Phuong Thi Quy Le, Michele Ann McTigue, Cynthia Louise Palmer, Paul Francis Richardson, Neal William Sach
  • Publication number: 20140135339
    Abstract: The invention relates to compounds of formula (?) as further defined herein and to the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to the uses thereof. The compounds and salts of the present invention inhibit anaplastic lymphoma kinase (ALK) and/or EML4-ALK and are useful for treating or ameliorating abnormal cell proliferative disorders, such as cancer.
    Type: Application
    Filed: January 15, 2014
    Publication date: May 15, 2014
    Applicant: PFIZER INC.
    Inventors: Simon Bailey, Benjamin Joseph Burke, Michael Raymond Collins, Jingrong Jean Cui, Judith Gail Deal, Robert Louis Hoffman, Qinhua Huang, Ted William Johnson, Robert Steven Kania, John Charles Kath, Phuong Thi Quy Le, Michele Ann McTigue, Cynthia Louise Palmer, Paul Francis Richardson, Neal William Sach
  • Patent number: 8680111
    Abstract: The invention relates to compounds of formula (?) as further defined herein and to the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to the uses thereof. The compounds and salts of the present invention inhibit anaplastic lymphoma kinase (ALK) and/or EML4-ALK and are useful for treating or ameliorating abnormal cell proliferative disorders, such as cancer.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: March 25, 2014
    Assignee: Pfizer Inc.
    Inventors: Simon Bailey, Benjamin Joseph Burke, Michael Raymond Collins, Jingrong Jean Cui, Judith Gail Deal, Robert Louis Hoffman, Qinhua Huang, Ted William Johnson, Robert Steven Kania, John Charles Kath, Phuong Thi Quy Le, Michele Ann McTigue, Cynthia Louise Palmer, Paul Francis Richardson, Neal William Sach
  • Patent number: 8119624
    Abstract: The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt or solvate thereof, wherein: Ring A is (4-12)-membered heterocyclyl; Ring B is a fused benzene ring selected from the group consisting of: Ring A, ring B, ring C, R1, R1a, R2, R3, R4, L2, n, t, w, and z are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of glucokinase, the method comprising administering to a mammal an effective amount of a compound of formula (I).
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: February 21, 2012
    Assignee: Pfizer Inc.
    Inventors: Hao Bai, Simon Bailey, Dilip Ramakant Bhumralkar, Feng C. Bi, Fengli Guo, Mingying He, Paul Stuart Humphries, Anthony Lai Ling, Jihong Lou, Seiji Nukui, Ru Zhou
  • Publication number: 20110039821
    Abstract: The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt or solvate thereof, wherein: Ring A is (4-12)-membered heterocyclyl; Ring B is a fused benzene ring selected from the group consisting of: Ring A, ring B, ring C, R1, R1a, R2, R3, R4, L2, n, t, w, and z are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of glucokinase, the method comprising administering to a mammal an effective amount of a compound of formula (I).
    Type: Application
    Filed: October 27, 2010
    Publication date: February 17, 2011
    Inventors: Hao Bai, Simon Bailey, Dilip Ramakant Bhumralkar, Feng C. Bi, Fengli Guo, Mingying He, Paul Stuart Humphries, Anthony Lai Ling, Jihong Lou, Seiji Nukui, Ru Zhou
  • Patent number: 7842713
    Abstract: The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt or solvate thereof, wherein: Ring A is (4-12)-membered heterocyclyl; Ring B is a fused benzene ring selected from the group consisting of: Ring A, ring B, ring C, R1, R1a, R2, R3, R4, L2, n, t, w, and z are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of glucokinase, the method comprising administering to a mammal an effective amount of a compound of formula (I).
    Type: Grant
    Filed: May 9, 2007
    Date of Patent: November 30, 2010
    Assignee: Pfizer Inc
    Inventors: Hao Bai, Simon Bailey, Dilip Ramakant Bhumralkar, Feng C. Bi, Fengli Guo, Mingying He, Paul Stuart Humphries, Anthony Lai Ling, Jihong Lou, Seiji Nukui, Ru Zhou
  • Publication number: 20090131397
    Abstract: The present application is directed to a new class of isoxazoles and their use as estrogen modulators.
    Type: Application
    Filed: October 31, 2008
    Publication date: May 21, 2009
    Inventors: Simon Bailey, Stephen Douglas Barrett, Larry Don Bratton, Stephen Alan Fakhoury, Sandra Marie Jennings, Lorna Helen Mitchell, Raj Kumar Raheja, Veerabahu Shanmugasundaram
  • Patent number: 7470715
    Abstract: The present application is directed to a new class of isoxazoles and their use as estrogen modulators.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: December 30, 2008
    Assignee: Pfizer Inc.
    Inventors: Simon Bailey, Stephen Douglas Barrett, Raj Kumar Raheja, Veerabahu Shanmugasundaram
  • Publication number: 20080280875
    Abstract: The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt or solvate thereof, wherein: Ring A is (4-12)-membered heterocyclyl; Ring B is a fused benzene ring selected from the group consisting of: Ring A, ring B, ring C, R1, R1a, R2, R3, R4, L2, n, t, w, and z are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of glucokinase, the method comprising administering to a mammal an effective amount of a compound of formula (I).
    Type: Application
    Filed: May 9, 2007
    Publication date: November 13, 2008
    Inventors: Hao Bai, Simon Bailey, Dilip Ramakant Bhumralkar, Feng C. Bi, Fengli Guo, Mingying He, Paul Stuart Humphries, Anthony Lai Ling, Jihong Lou, Seiji Nukul, Ru Zhou
  • Patent number: D1007554
    Type: Grant
    Filed: June 16, 2021
    Date of Patent: December 12, 2023
    Assignee: Optima Low Vision Services Ltd.
    Inventors: John Collins, Nicholas Collins, Austen Miller, Simon Bailey
  • Patent number: D1054835
    Type: Grant
    Filed: October 6, 2020
    Date of Patent: December 24, 2024
    Assignee: LES PRODUITS SUNFORCE INC.
    Inventors: Michael Dahan, Simon Bailey