Patents by Inventor Simon Blake

Simon Blake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RESISTIN ANTAGONISTS AND THEIR USE
    Publication number: 20110071277
    Abstract: Resistin antagonists, including antibodies reactive with defined epitopes, are disclosed. Antigens useful for raising antibodies against human resistin are also disclosed. Methods of utilizing resistin antagonists to treat or alleviate the symptoms of the diseases with aberrant fibroblast activity including interstitial lung diseases, hypertrophic scarring, keloid scarring and scleroderma are also disclosed. Methods of utilizing resistin as a biomarker to diagnose the risk and/or progression of osteoarthritis are also disclosed. Further disclosed are methods of utilizing the antagonists to treat or alleviate the symptoms of osteoarthritis.
    Type: Application
    Filed: March 12, 2010
    Publication date: March 24, 2011
    Inventors: Simon Blake, Jill Carton, Jennifer Henrica Lee, Keying Ma, Paul Marsters, Kristen Picha, Xiao-Yu R. Song, Francis Farrell, Lynne Murray, Alexey Teplyakov, Tatiana Ort
  • RESISTIN ANTAGONISTS AND THEIR USE
    Publication number: 20090162375
    Abstract: Resistin antagonists, including antibodies reactive with defined epitopes, are disclosed. Antigens useful for raising antibodies against human resistin are also disclosed. Methods of utilizing resistin antagonists to treat or alleviate the symptoms of the diseases with aberrant fibroblast activity including interstitial lung diseases, hypertrophic scarring, keloid scarring and scleroderma are also disclosed. Methods of utilizing resistin as a biomarker to diagnose the risk and/or progression of osteoarthritis are also disclosed. Further disclosed are methods of utilizing the antagonists to treat or alleviate the symptoms of osteoarthritis.
    Type: Application
    Filed: October 25, 2007
    Publication date: June 25, 2009
    Inventors: Simon Blake, Jill Carton, Jennifer Henrica Lee, Keying Ma, Paul Marsters, Kristen Picha, Xiao-Yu R. Song, Francis Farrell, Lynne Murray, Alexey Teplyakov, Tatiana Ort
  • Use of Toll-Like Receptor 4 Antagonists for the Treatment or Prevention of Osteoarthritic Conditions
    Publication number: 20090136509
    Abstract: Methods for treating or preventing osteoarthric conditions using Toll-Like Receptor 4 (TLR4) antagonists are disclosed.
    Type: Application
    Filed: October 31, 2008
    Publication date: May 28, 2009
    Inventors: Simon Blake, Vedrana Stojanovic-Susulic, Mark Ware, Linda Wu