Abstract: A drug delivery device for conducting a medical therapy includes a housing with an exit port opening, and an exit port assembly, where said exit port assembly includes a rigid exit port sealing holder and a soft exit port sealing, and provides both a fluid-tight closure of the exit port opening and a fluid-tight connection between the housing and the rigid exit port sealing holder.

Abstract: A drug delivery device for conducting a medical therapy includes a housing with an exit port opening, and an exit port assembly, where said exit port assembly includes a rigid exit port sealing holder and a soft exit port sealing, and provides both a fluid-tight closure of the exit port opening and a fluid-tight connection between the housing and the rigid exit port sealing holder.

Abstract: A bone fracture fixation system including reference pins inserted into bone fragments of a patient in a first configuration and an image capture device configured to capture an image of the reference pins, and the bone fragments. The system includes a processor configured to receive and pre-process the captured image data. The processor pre-processes the image data by virtually re-positioning the reference pins in the first configuration into a second configuration, wherein the re-positioning virtually re-positions the bone fragments into normal alignment; and virtually generating a support device. The system includes a point-of-care production apparatus that produces a three-dimensional model of the virtually generated support device in a form that can be applied to the patient.

Abstract: A module for a drug delivery device includes a first housing portion with a bearing element for supporting a neck or head portion of a first end of a reservoir and a second housing portion with an elastic contact element for supporting a second end of the reservoir opposite the first end. The first and second housing portions are configured to couple to each other in an assembled state in which the first and second housing portions form a cavity for accommodating the reservoir. The bearing element and the elastic contact element may each define a limiter or limiting structure of the cavity in a longitudinal direction of the cavity to secure or hold the reservoir free of play within the cavity. The elastic contact element may be is injection molded onto a surface of a body of the second housing portion.

Abstract: A bone graft containment device includes a body extending longitudinally from a first end to a second end. The body is defined via a strut framework sized and shaped to correspond to an outer surface of a target bone. The strut framework defines an interior space configured to receive a bone graft or bone graft substitute material. The device also includes a first grasping structure and a second grasping structure extending from an exterior of the body. The first and second grasping structures are configured to receive a bone fixation plate therebetween.

Abstract: A modular, semi-disposable patch pump for conducting a medical therapy includes a pump unit releasably connected to a reservoir unit by means of a bayonet connection; and a housing design for supporting both reliability and ease of use of said connection.

Abstract: A drug delivery device for conducting a medical therapy includes a housing with an exit port opening, and an exit port assembly, where said exit port assembly includes a rigid exit port sealing holder and a soft exit port sealing, and provides both a fluid-tight closure of the exit port opening and a fluid-tight connection between the housing and the rigid exit port sealing holder.

Abstract: A fill port for filling a liquid medicament into a reservoir located inside a drug delivery device includes insert fixed in a passage of a wall of the drug delivery device, and a pierceable fill port sealing is sandwiched between the insert and both the housing of the drug delivery device and the reservoir to provide a fluid-tight sealing between the reservoir and the housing.

Abstract: A bone fracture fixation system including reference pins inserted into bone fragments of a patient in a first configuration and an image capture device configured to capture an image of the reference pins, and the bone fragments. The system includes a processor configured to receive and pre-process the captured image data. The processor pre-processes the image data by virtually re-positioning the reference pins in the first configuration into a second configuration, wherein the re-positioning virtually re-positions the bone fragments into normal alignment; and virtually generating a support device. The system includes a point-of-care production apparatus that produces a three-dimensional model of the virtually generated support device in a form that can be applied to the patient.

Abstract: A bone plate includes at least one variable angle locking hole that is configured to threadedly mate with a variable angle locking screw oriented so as to define any angle among a range of angles with respect to a central axis of the VA locking hole at which a threaded head of the locking screw is configured to threadedly purchase with the bone plate in the variable angle locking hole.

Abstract: A bone fracture fixation system including reference pins inserted into bone fragments of a patient in a first configuration and an image capture device configured to capture an image of the reference pins, and the bone fragments. The system includes a processor configured to receive and pre-process the captured image data. The processor pre-processes the image data by virtually re-positioning the reference pins in the first configuration into a second configuration, wherein the re-positioning virtually re-positions the bone fragments into normal alignment; and virtually generating a support device. The system includes a point-of-care production apparatus that produces a three-dimensional model of the virtually generated support device in a form that can be applied to the patient.

Abstract: A bone plate includes at least one variable angle locking hole that is configured to threadedly mate with a variable angle locking screw oriented so as to define any angle among a range of angles with respect to a central axis of the VA locking hole at which a threaded head of the locking screw is configured to threadedly purchase with the bone plate in the variable angle locking hole.

Abstract: A bone fracture fixation system including reference pins inserted into bone fragments of a patient in a first configuration and an image capture device configured to capture an image of the reference pins, and the bone fragments. The system includes a processor configured to receive and pre-process the captured image data. The processor pre-processes the image data by virtually re-positioning the reference pins in the first configuration into a second configuration, wherein the re-positioning virtually re-positions the bone fragments into normal alignment; and virtually generating a support device. The system includes a point-of-care production apparatus that produces a three-dimensional model of the virtually generated support device in a form that can be applied to the patient.

Abstract: A bone plate includes at least one variable angle locking hole that is configured to threadedly mate with a variable angle locking screw oriented so as to define any angle among a range of angles with respect to a central axis of the VA locking hole at which a threaded head of the locking screw is configured to threadedly purchase with the bone plate in the variable angle locking hole.

Abstract: A bone graft containment device includes a body extending longitudinally from a first end to a second end. The body is defined via a strut framework sized and shaped to correspond to an outer surface of a target bone. The strut framework defines an interior space configured to receive a bone graft or bone graft substitute material. The device also includes a first grasping structure and a second grasping structure extending from an exterior of the body. The first and second grasping structures are configured to receive a bone fixation plate therebetween.