Abstract: The present disclosure relates to methods and systems of spray calibration and measurement. The method including selecting a nozzle-agrochemical combination to perform at least one of reducing at least one of resistance development in a pest species, reducing phytotoxicity in a crop plant, maximizing effective dose, and reducing off target effects. The method may further include obtaining a target area having a target zone and an off-target zone and spraying for a time (T), a volume (V), of a liquid composition through a test nozzle, at a height (H) from the test nozzle to the target surface, and at the target zone of the target surface.