Patents by Inventor Simon Charles Barry

Simon Charles Barry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF
    Publication number: 20250101080
    Abstract: The present invention relates to chimeric antigen receptors (CARs) directed to cells expressing a dysfunctional or non-functional P2X purinoceptor 7 receptor. Further provided are methods of targeting neoplastic cells and tumours expressing a dysfunctional or non-functional P2X purinoceptor 7 receptor and methods of treating and preventing cancer is a subject.
    Type: Application
    Filed: July 24, 2024
    Publication date: March 27, 2025
    Inventors: Justin Taylor Coombs, Simon Charles Barry, Timothy John Sadlon
  • Chimeric antigen receptors and uses thereof
    Patent number: 12121539
    Abstract: The present invention relates to chimeric antigen receptors (CARs) directed to cells expressing a dysfunctional or non-functional P2X purinoceptor 7 receptor. Further provided are methods of targeting neoplastic cells and tumours expressing a dysfunctional or non-functional P2X purinoceptor 7 receptor and methods of treating and preventing cancer is a subject.
    Type: Grant
    Filed: September 10, 2016
    Date of Patent: October 22, 2024
    Assignee: BIOSCEPTRE (AUST) PTY LTD
    Inventors: Justin Taylor Coombs, Simon Charles Barry, Timothy John Sadlon
  • CHIMERIC ANTIGEN RECEPTOR T CELL AND METHOD
    Publication number: 20240033356
    Abstract: N(57) Abstract: There is a need for new and alternative options for immune therapy of proliferative diseases such as cancer. This need C\11 may be address by providing a chimeric antigen receptor having an extracellular domain including a binding domain which recognises Nthe cancer-stem-cell-associated protein Lgr5; a transmembrane domain; and an intracellular signalling domain that activates a cellular .,, function. Such CAR T cells can be used to kill cancer cells and treat or prevent cancer in a subject.
    Type: Application
    Filed: November 18, 2021
    Publication date: February 1, 2024
    Inventors: Justin Taylor COOMBS, Shaun Reuss MCCOLL, Simon Charles BARRY
  • CHIMERIC ANTIGEN RECEPTORS WITH MODIFIED LINKER DOMAINS AND USES THEREOF
    Publication number: 20220089718
    Abstract: The present invention relates to an optimized chimeric antigen receptor (CAR), and genetically modified cells expressing the same, that can target a diverse range of cancer types. More specifically, the CAR has an optimized linker length that facilitates the targeting and lyse of a wide range of cancer cell types by CAR expressing T cells.
    Type: Application
    Filed: May 20, 2019
    Publication date: March 24, 2022
    Inventors: Kanchana Veronika Bandara, Justin Taylor Coombs, Timothy John Sadlon, Simon Charles Barry, Jade Hui Yu Foeng, Shaun Reuss McColl