Patents by Inventor Simon Charles Dolan

Simon Charles Dolan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6239287
    Abstract: A process for the preparation of the phosphonium compound of formula (1), which comprises reacting N-phenylpyrrolidinone (II), with pyridinium bromide perbromide, in the presence of a tertiary organic base and a suitable lewis acid and then treating the resultant bromo derivative (III) with the phosphine (IV, R1R2R1P) and the use of compound (I) when so prepared for the preparation of the glycine antagonist.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: May 29, 2001
    Assignee: Glaxo Wellcome SpA
    Inventors: Simon Charles Dolan, Paolo Maragni, Alcide Perboni
  • Patent number: 5981572
    Abstract: The invention thus provides compounds of Formula (I) ##STR1## wherein R.sup.1 and R.sup.2 which may be the same or different represent H, C.sub.1-6 alkyl or substituted alkyl or C.sub.3-7 cycloalkyl; or aryl;R.sup.3, and R.sup.4 which may be the same or different represent H, halogen, C.sub.1-6 alkyl; or substituted aryl;R.sup.5 is H or C.sub.1-6 alkyl;n is an integer 0, 1 or 2and m is an integer 1, 2, 3, or 4;the dotted line indicates the presence or absence of an additional bond; and pharmaceutically acceptable solvates (e.g. hydrates) thereof.
    Type: Grant
    Filed: November 6, 1998
    Date of Patent: November 9, 1999
    Assignee: Glaxo Wellcome Inc.
    Inventors: Frank Ellis, Terence Aaron Panchal, Peter Charles North, Jason William Beames Cooke, Simon Charles Dolan