Patents by Inventor Simon D. P. Baugh

Simon D. P. Baugh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and Methods for Treating or Preventing Heart Failure
    Publication number: 20220096450
    Abstract: The present invention relates to the discovery of compounds that can be used to treat and/or prevent heart failure in a subject. In certain embodiments, the compounds of the invention are sulfide:quinone oxidoreductase (SQOR) inhibitors. In other embodiments, the compounds of the invention increase physiological levels of H2S in the subject. In yet other embodiments, administration of the compounds of the invention treats, ameliorates, and/or prevents hypertension, and/or atherosclerosis, and/or pathological cardiac remodeling that leads to heart failure in the subject.
    Type: Application
    Filed: January 9, 2020
    Publication date: March 31, 2022
    Inventors: Marilyn S. JORNS, Michael R. JACKSON, Kristie D. COX, Patrick Y. S. LAM, Simon D. P. BAUGH
  • METHODS OF TREATING AUTOIMMUNE AND INFLAMMATORY DISEASES AND DISORDERS
    Publication number: 20110082178
    Abstract: Heterocyclic compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed.
    Type: Application
    Filed: October 13, 2010
    Publication date: April 7, 2011
    Applicant: LEXICON PHARMACEUTICALS, INC.
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Simon D.P. Baugh, Kenneth G. Carson, Theodore C. Jessop, James E. Tarver
  • Heterocyclic compounds, compositions comprising them and methods of their use
    Patent number: 7825142
    Abstract: Heterocyclic compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed.
    Type: Grant
    Filed: August 24, 2009
    Date of Patent: November 2, 2010
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Simon D. P. Baugh, Kenneth G. Carson, Theodore C. Jessop, James E. Tarver
  • HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND METHODS OF THEIR USE
    Publication number: 20090312375
    Abstract: Heterocyclic compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed.
    Type: Application
    Filed: August 24, 2009
    Publication date: December 17, 2009
    Applicant: LEXICON PHARMACEUTICALS, INC.
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Simon D.P. Baugh, Kenneth G. Carson, Theodore C. Jessop, James E. Tarver
  • Heterocyclic compounds, compositions comprising them and methods of their use
    Patent number: 7598280
    Abstract: Heterocyclic compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: October 6, 2009
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Simon D. P. Baugh, Kenneth G. Carson, Theodore C. Jessop, James E. Tarver
  • Heterocyclic Compounds, Compositions Comprising Them and Methods of Their Use
    Publication number: 20090030050
    Abstract: Heterocyclic compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed.
    Type: Application
    Filed: February 28, 2008
    Publication date: January 29, 2009
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Simon D.P. Baugh, Kenneth G. Carson, Theodore C. Jessop, James E. Tarver
  • Methods and compositions for the treatment of body composition disorders
    Publication number: 20080200458
    Abstract: This invention relates to methods of treating, managing and preventing body composition disorders, and to compounds and pharmaceutical compositions useful in such methods.
    Type: Application
    Filed: January 17, 2008
    Publication date: August 21, 2008
    Inventors: Joseph Barbosa, Simon D.P. Baugh, Qiang Han, Victoria K. Lombardo, Huy Van Nguyen, Praveen K. Pabba, Kristen M. Terranova
  • Methods and compositions for the treatment of pain, inflammation and cancer
    Publication number: 20080194557
    Abstract: This invention relates to methods of treating, managing and preventing pain, inflammation, cancer, and ocular diseases and disorders, and to compounds and pharmaceutical compositions useful in such methods.
    Type: Application
    Filed: January 17, 2008
    Publication date: August 14, 2008
    Inventors: Joseph Barbosa, Simon D.P. Baugh, Qiang Han, Victoria K. Lombardo, Huy Van Nguyen, Praveen K. Pabba, Kristen M. Terranova
  • Beta-cyclodextrin dimers and phthalocyanines and uses thereof
    Publication number: 20030134824
    Abstract: The invention provides &bgr;-cyclodextrin dimers and phthalocyanines which can be used in photodynamic therapy of cancer.
    Type: Application
    Filed: November 12, 2001
    Publication date: July 17, 2003
    Inventors: Ronald Breslow, Simon D.P. Baugh