Patents by Inventor Simon David Peter Baugh

Simon David Peter Baugh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for inhibiting ACSS2
    Patent number: 12077527
    Abstract: The present invention provides compositions and methods for inhibiting ACSS2 for modulating histone acetylation or for treating or preventing a neurological disease or disorder.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: September 3, 2024
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Philipp Mews, Shelley L Berger, Jeffrey D. Winkler, Andrew Glass, Simon David Peter Baugh
  • NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE
    Publication number: 20240018121
    Abstract: Pharmaceutical compositions include heteroaromatic compounds having a disease-modifying action in the treatment of fungal infections and diseases associated with fungal infection.
    Type: Application
    Filed: June 3, 2021
    Publication date: January 18, 2024
    Applicant: FOX CHASE CHEMCIAL DIVERSITY CENTER, INC.
    Inventors: Simon David Peter BAUGH, Kathryn B. FREEMAN, Jeffrey Claude PELLETIER, Allen B. REITZ, Richard W. SCOTT, Garry Robert SMITH, Sandeep THANNA, Damian G. WEAVER, David B. WHITMAN
  • COMPOSITIONS AND METHODS FOR INHIBITING ACSS2
    Publication number: 20200291005
    Abstract: The present invention provides compositions and methods for inhibiting ACSS2 for modulating histone acetylation or for treating or preventing a neurological disease or disorder.
    Type: Application
    Filed: September 26, 2018
    Publication date: September 17, 2020
    Inventors: Philipp MEWS, Shelley L. BERGER, Jeffrey D. WINKLER, Andrew GLASS, Simon David Peter Baugh
  • Antivirals against molluscum contagiosum virus
    Patent number: 10112895
    Abstract: This invention provides compounds of formulas (I)-(XIV) as defined in the specification, and pharmaceutical compositions comprising the same, and methods of inhibiting, treating, or abrogating a molluscum contagiosum virus infection in a subject using compounds or compositions of the invention:
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: October 30, 2018
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Robert P. Ricciardi, Allen B. Reitz, Michael H. Parker, Simon David Peter Baugh, Manunya Nuth, Hancheng Guan
  • NOVEL ANTIVIRAL AGENTS AGAINST HBV INFECTION
    Publication number: 20180230092
    Abstract: The present invention is directed toward novel compounds and novel methods of use of said compounds of the formula (I), useful as nucleocapsid assembly inhibitors for the treatment of viruses, especially but not exclusively, including pregenomic RNA encapsidation inhibitors of HBV for the treatment of Hepatitis B virus (HBV) infection and related conditions. including hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof, wherein A, R1, R2, R3, R4, R5, R6, R7, and R8 are defined herein.
    Type: Application
    Filed: March 22, 2018
    Publication date: August 16, 2018
    Inventors: XIAODONG XU, JU-TAO GUO, TONG XIAO, YANMING DU, TIMOTHY BLOCK, SIMON DAVID PETER BAUGH, HONG YE
  • Antiviral agents against HBV infection
    Patent number: 9938236
    Abstract: The present invention provides novel compounds of formula (I) and methods of use thereof. In certain embodiments, the compounds of the invention are useful as nucleocapsid assembly inhibitors. In other embodiments, the compounds of the invention are useful as pregenomic RNA encapsidation inhibitors of Hepatitis B virus (HBV). In yet other embodiments, the compounds of the invention are useful for the treatment of viral infection, including HBV and related viral infections.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: April 10, 2018
    Assignees: Drexel University, Baruch S. Blumberg Institute, Arbutus Biopharma, Inc.
    Inventors: Xiaodong Xu, Ju-Tao Guo, Tong Xiao, Yanming Du, Timothy Block, Simon David Peter Baugh, Hong Ye
  • ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS
    Publication number: 20170217882
    Abstract: This invention provides compounds of formulas (I)-(XIV) as defined in the specification, and pharmaceutical compositions comprising the same, and methods of inhibiting, treating, or abrogating a molluscum contagiosum virus infection in a subject using compounds or compositions of the invention:
    Type: Application
    Filed: September 28, 2015
    Publication date: August 3, 2017
    Inventors: Robert P. RICCIARDI, Allen B. REITZ, Michael H. PARKER, Simon David Peter BAUGH
  • NOVEL ANTIVIRAL AGENTS AGAINST HBV INFECTION
    Publication number: 20160024004
    Abstract: The present invention provides novel compounds of formula (I) and methods of use thereof. In certain embodiments, the compounds of the invention are useful as nucleocapsid assembly inhibitors. In other embodiments, the compounds of the invention are useful as pregenomic RNA encapsidation inhibitors of Hepatitis B virus (HBV). In yet other embodiments, the compounds of the invention are useful for the treatment of viral infection, including HBV and related viral infections.
    Type: Application
    Filed: December 27, 2013
    Publication date: January 28, 2016
    Inventors: XIAODONG XU, JU-TAO GUO, TONG XIAO, YANMING DU, TIMOTHY BLOCK, SIMON DAVID PETER BAUGH, HONG YE
  • MST1 KINASE INHIBITORS AND METHODS OF THEIR USE
    Publication number: 20140051681
    Abstract: Compounds for the inhibition of mammalian Ste20-like kinase 1 (MST1) are disclosed, along with compositions comprising them and methods of their use in the treatment, management or prevention of an inflammatory or autoimmune diseases or disorders.
    Type: Application
    Filed: May 3, 2013
    Publication date: February 20, 2014
    Inventors: David John AUGERI, Jeffrey Thomas BAGDANOFF, Simon David Peter BAUGH, Marianne CARLSEN, Kenneth Gordon CARSON, John Anthony GILLERAN, Wei HE, Tamas ORAVECZ, Konstantin SALOJIN, Leonard SUNG
  • MST1 kinase inhibitors and methods of their use
    Patent number: 8440652
    Abstract: Compounds for the inhibition of mammalian Ste20-like kinase 1 (MST1) are disclosed, along with compositions comprising them and methods of their use in the treatment, management or prevention of an inflammatory or autoimmune diseases or disorders.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: May 14, 2013
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: David John Augeri, Jeffrey Thomas Bagdanoff, Simon David Peter Baugh, Marianne Carlsen, Kenneth Gordon Carson, John Anthony Gilleran, Wei He, Tamas Oravecz, Konstantin Salojin, Leonard Sung
  • MST1 KINASE INHIBITORS AND METHODS OF THEIR USE
    Publication number: 20120225857
    Abstract: Compounds for the inhibition of mammalian Ste20-like kinase 1 (MST1) are disclosed, along with compositions comprising them and methods of their use in the treatment, management or prevention of an inflammatory or autoimmune diseases or disorders.
    Type: Application
    Filed: March 2, 2012
    Publication date: September 6, 2012
    Inventors: David John Augeri, Jeffrey Thomas Bagdanoff, Simon David Peter Baugh, Marianne Carlsen, Kenneth Gordon Carson, John Anthony Gilleran, Wei He, Tamas Oravecz, Konstantin Salojin, Leonard Sung