Abstract: Systems and method to measure pressure are described herein. The system can include a force sensor can that be implanted into a patient to measure, for example, cardiac pressure. The force sensor can include first and second film layers that can define a plurality of pressure cells. An external pressure can deform the pressure cells and change their resonant frequency. When exposed to an acoustic signal, the pressure cells can resonant at a pressure-dependent resonant frequency. The system can detect reflected acoustic waves generated by the resonance of the pressure cells. The system can convert the frequency readings into pressure values.

Abstract: Systems and methods for occluding a body cavity including providing an implantable void-filling device, wherein the implantable void-filling device includes an inflatable implant that defines an interior of the implantable void-filling device. The inflatable implant is capable of being filled with an inflation material to cause the inflatable implant to expand from a collapsed configuration to an expanded configuration. The implantable void-filling device also includes a connection hub attached to an exterior surface of the inflatable implant and a plurality of independent anchors coupled to and extending out from the connection hub along the length of the inflatable implant, such that the plurality of anchors collectively surround the inflatable implant. The connection hub and anchors are configured such that expansion of the anchors away from the surface of the inflatable implant anchors the void filling device to a body tissue.

Abstract: Transcatheter stent valve implants and implants that preserve functional caliber of the left ventricle outflow tract, LVOT, and streamlined blood flow from left ventricular inflow to the LVOT. The implants have inflatable balloons that prevent regurgitation around the device and allow more accurate sizing and fit.

Abstract: The present disclosure describes a system and a method for producing patient-specific small diameter vascular grafts (SDVG) for coronary artery bypass graft (CABG) surgery. In some embodiments, the method for producing SDVGs includes non-invasive quantification of patient-specific coronary and vascular physiology by applying computational fluid dynamics (CFD), rapid prototyping, and in vitro techniques to medical images and coupling the quantified patient-specific coronary and vascular physiology from the CFD to computational fluid-structure interactions and SDVG structural factors to design a patient-specific SDVG.

Abstract: The present disclosure describes a device that can be implanted into the left atrial appendage for occlusion. The device can prevent or reduce thrombus formation in this anatomic region for patients with atrial fibrillation. This device includes a patient-specific inflatable device that represents a patient's anatomy or morphological class. The inflatable device can be designed by imaging (e.g., computed tomography, magnetic resonance imaging) the patient's anatomy. Through a catheter (or surgically), the inflatable device can be filled with an inflation fluid to occlude the appendage in a patient-specific fashion.