Abstract: The disclosure provides pharmaceutical compositions comprising Efruxifermin, processes for preparing lyophilized compositions, and methods of use for treating nonalcoholic steatohepatitis (NASH), nonalcoholic fatty liver disease (NAFL), alcoholic steatohepatitis (ASH), alcoholic liver disease (ALD) or alcoholic fatty liver disease (AFL), type 2 diabetes, obesity, hypertriglyceridemia, dyslipidemia, protein misfolding disease, alcohol-related and other cravings or addictions, reversing liver cirrhosis or reducing fibrosis associated with NASH, ASH, ALD AFL, or protein misfolding disease, normalizing liver fat content, reducing elevated blood glucose, increasing insulin sensitivity, and/or reducing uric acid levels.

Abstract: The invention relates to a method for gripping an object by a handling system, including a robot with at least one robot arm, a gripping device which is connected to the robot arm and has a pneumatically operated suction gripper having an elastically deformable contact portion for contact with an outer surface of the object to be gripped, an identifier for identifying the outer surface of the object to be gripped and a controller which interacts with the identifier and is designed to control the robot.

Abstract: The invention relates to a handling device for handling objects, including a base unit which extends overall in an elongate manner along a base axis from a first end to a second end, wherein a flange portion is arranged at the first end for fastening the handling device to a robot arm and wherein a pivot unit having a pivot portion is arranged at the second end, wherein the pivot portion is mounted so as to be pivotable about a pivot axis by a pivot joint, wherein the base unit has a pneumatic cylinder which is designed to pivot the pivot portion about the pivot axis, and including a couplable or coupled, pneumatically operated end effector for gripping an object.

Abstract: The present invention relates to compositions comprising a therapeutic protein with enhanced stability, which comprise a piperazine- or morpholine-containing zwitterionic buffering substance, such as HEPES, in particular when used out of the common pH range. The compositions of the invention are particularly useful for topical administration The present invention further relates to the use of said compositions for treating bacterial infections, e.g. bacterial infections caused by Staphylococcus aureus such as methicillin-resistant Staphylococcus aureus (MRSA). The present invention further relates to the use of said compositions for preventing or eliminating nasal bacterial colonization or bacterial colonization of the skin.

Abstract: The invention relates to a method for gripping an object by a handling system, including a robot with at least one robot arm, a gripping device which is connected to the robot arm and has a pneumatically operated suction gripper having an elastically deformable contact portion for contact with an outer surface of the object to be gripped, an identification means for identifying the outer surface of the object to be gripped and a control means which interacts with the identification means and is designed to control the robot, wherein an outer surface of an object to be gripped is identified, wherein a distinction is made between planar portions of the outer surface on the one hand and convex elevations or outer edges on the other, and wherein the suction gripper is made to approach the outer surface of the object to be gripped in such a way that at least a part of the contact portion of the suction gripper clings to a convex elevation or outer edge of the outer surface.

Abstract: The invention relates to a handling device for handling objects, including a base unit which extends overall in an elongate manner along a base axis from a first end to a second end, wherein a flange portion is arranged at the first end for fastening the handling device to a robot arm and wherein a pivot unit having a pivot portion is arranged at the second end, wherein the pivot portion is mounted so as to be pivotable about a pivot axis by means of a pivot joint, wherein the base unit has a pneumatic cylinder which is designed to pivot the pivot portion about the pivot axis, and including a couplable or coupled, pneumatically operated end effector for gripping an object, wherein the base unit includes an integrated negative-pressure generator and is constructed as a structural unit with its own module housing, wherein the module housing is designed to extend in an elongate manner along the base axis and in particular surrounds the pneumatic cylinder and the negative-pressure generator.